Evidence map›Paper›PMID 33103016›Full record

ArticleCurrent opinion in physiology2020

Calcium regulation of T cell metabolism

Yinhu Wang, Anthony Tao, Martin Vaeth, Stefan Feske

Open access · greenAbstract read
In one paragraph

Article in Current opinion in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. EZH2 and intracellular CaCellular & molecular immunology · 2026
    Article
  5. CRAC channels as targets for immunotherapy.Current opinion in immunology · 2026
    Review
  6. Baohuoside I CombatedAntioxidants (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. METTL14 MediatesRedox report : communications in free radical research · 2025
    Article
  12. Journal of human immunity · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Human CD4iScience · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yinhu WangDepartment of Pathology, New York University School of Medicine, New York, NY, USA.
Anthony TaoDepartment of Pathology, New York University School of Medicine, New York, NY, USA.
Martin VaethInstitute of Systems Immunology, Julius Maximilians University of Würzburg, Würzburg, Germany.
Stefan FeskeDepartment of Pathology, New York University School of Medicine, New York, NY, USA.
New York University · USUniversity of Würzburg · DE

Funding

CRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6M
Ca2+ signaling via SOCE in the pathogenesis of Sjögren’s syndromeR01DE027981 · NIDCR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN, LACRUZ, RODRIGO S. · 2019 to 2023
$2.7M
Regulation of Follicular T cell Responses in the Lung by Ion ChannelsR01AI130143 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2017 to 2021
$2.4M
Regulation of encephalitogenic T cells by CRAC channelsR01AI137004 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2018 to 2022
$2.4M
Calcium channel CACNB1 in T cell function and immunityR03TR002873 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2019 to 2019
$170k
NCATS NIH HHS R03 TR002873NIAID NIH HHS R01 AI097302NIAID NIH HHS R01 AI130143NIAID NIH HHS R01 AI137004NIDCR NIH HHS R01 DE027981
6 · The paper itself

Abstract

T cells are an essential component of the immune system that provide antigen-specific acute and long lasting immune responses to infections and tumors, ascertain the maintenance of immunological tolerance and, on the flipside, mediate autoimmunity in a variety of diseases. The activation of T cells through antigen recognition by the T cell receptor (TCR) results in transient and sustained Ca

Identifiers

PMID33103016
PMCPMC7584116
OpenAlexW3067209413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.