Evidence map›Paper›PMID 33102928›Full record

ArticleChem2020

Creation of Bacterial cells with 5-Hydroxytryptophan as a 21

Yuda Chen, Juan Tang, Lushun Wang, Zeru Tian, Adam Cardenas, Xinlei Fang, Abhishek Chatterjee, Han Xiao

Open access · bronzeAbstract read
In one paragraph

Article in Chem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  4. In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins.Chembiochem : a European journal of chemical biology · 2025
    Review
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  9. BeyondChemical reviews · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuda ChenDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Juan TangDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Lushun WangDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Zeru TianDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Adam CardenasDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Xinlei FangDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Abhishek ChatterjeeDepartment of Chemistry, Boston College, 2609 Beacon Street, 246B Merkert Chemistry Center, Chestnut Hill, MA, 02467, U.S.A.
Han XiaoDepartment of Chemistry, Rice University, 6100 Main Street, Houston, Texas, 77005. U.S.A.
Rice University · USBoston College · US

Funding

A genetically encoded toolset to decipher the biology of post-translational modifications in the mammalian proteomeR35GM136437 · NIGMS · BOSTON COLLEGE · PI Abhishek Chatterjee · 2020 to 2026
$4.0M
Engineering Proteins with Noncanonical Amino AcidsR35GM133706 · NIGMS · RICE UNIVERSITY · PI Han Xiao · 2019 to 2026
$2.9M
NIGMS NIH HHS R35 GM133706NIGMS NIH HHS R35 GM136437
6 · The paper itself

Abstract

While most organisms utilize 20 canonical amino acid building blocks for protein synthesis, adding additional candidates to the amino acid repertoire can greatly facilitate the investigation and manipulation of protein structures and functions. In this study, we report the generation of completely autonomous organisms with a 21

Identifiers

PMID33102928
PMCPMC7583639
OpenAlexW3048735122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.