ArticleJGH open : an open access journal of gastroenterology and hepatology2020
Influence of sex on the association between body mass index and frequency of upper gastrointestinal symptoms.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Effectiveness of a formulary system on prophylactic oral proton pump inhibitors for drug-induced peptic ulcer in a Japanese tertiary hospital: an interrupted time series analysis.Journal of pharmaceutical health care and sciences · 2025Article
- Gastrointestinal symptoms in abused nonpatient women.BMC women's health · 2024Article
- Factors Associated with Overlap between Functional Dyspepsia and Nonerosive Reflux Disease in Endoscopy-based Helicobacter pylori-uninfected Japanese Health Checkup Participants: A Prospective, Multicenter Cross-sectional Study.Internal medicine (Tokyo, Japan) · 2024Article
- Functional Gastrointestinal Disorders and Abdominal Visceral Fat in Children and Adolescents.Pediatric gastroenterology, hepatology & nutrition · 2023Article
- Association Between Body Mass Index and Functional Dyspepsia in Young Japanese People.Journal of neurogastroenterology and motility · 2022Article
Corrections and comments
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Authors and funding
15 authors at 10 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimUpper gastrointestinal symptoms (UGSs), including reflux and dyspeptic symptoms (postprandial distress syndrome [PDS] and epigastric pain syndrome [EPS]), affect health-related quality of life. However, the influence of sex on the relationship between body mass index (BMI) and UGSs remains controversial. This study investigates the influence of sex on this association in healthy subjects. METHODS AND
resultsWe utilized the database of a prospective, multicenter, cohort study of 7112 subjects who underwent upper endoscopy for health screening. A multivariable logistic regression analysis was conducted to assess the association between BMI and UGSs stratified by sex, adjusting for clinical features. The influence of sex on the association between the overlapping of UGSs and BMI in symptomatic subjects was also investigated. Reflux symptoms were significantly associated with high BMI (multivariable odds ratio [OR] 1.36; 95% confidence interval [CI] 1.10-1.67,
conclusionsThe influence of BMI on the presence of UGSs was significantly different according to sex in this large-scale cohort.
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