Evidence map›Paper›PMID 33102751›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2020

Screening and follow-up of chronic liver diseases with understanding their etiology in clinics and hospitals.

Masahiro Ogawa, Atsunori Tsuchiya, Takayuki Watanabe, Toru Setsu, Naruhiro Kimura, Masato Matsuda, Yoshiki Hoshiyama, Hiroaki Saito, Tsutomu Kanazawa, Motoi Shiotani and 7 more

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. The pathogenesis of liver fibrosis in Wilson's disease: hepatocyte injury and regulation mediated by copper metabolism dysregulation.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Diagnosis and Therapeutic Management of Liver Fibrosis by MicroRNA.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Masahiro OgawaDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Atsunori TsuchiyaDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.ORCID https://orcid.org/0000-0002-9279-5917
Takayuki WatanabeDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Toru SetsuDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Naruhiro KimuraDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Masato MatsudaMedical Laboratory Division Niigata University Medical and Dental Hospital Niigata Japan.
Yoshiki HoshiyamaMedical Laboratory Division Niigata University Medical and Dental Hospital Niigata Japan.
Hiroaki SaitoDivision of Radiology, Department of Clinical Technology Niigata University Medical and Dental Hospital Niigata Japan.
Tsutomu KanazawaDivision of Radiology, Department of Clinical Technology Niigata University Medical and Dental Hospital Niigata Japan.
Motoi ShiotaniDepartment of Radiology and Radiation Oncology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.
Tatsuhiko SatoDepartment of Radiology and Radiation Oncology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.
Takuya YagiDepartment of Radiology and Radiation Oncology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.
Koji IgarashiBioscience Division TOSOH Corporation Ayase-shi Japan.
Norihiko YoshimuraDepartment of Radiology and Radiation Oncology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.
Masaaki TakamuraDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Hidefumi AoyamaDepartment of Radiology and Radiation Oncology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan.
Shuji TeraiDivision of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences Niigata University Niigata Japan.
Niigata University · JPNiigata University Medical and Dental Hospital · JPTosoh (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimConsidering the increasing prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH), the development of an effective screening and follow-up system that enables the recognition of etiological changes by primary physicians in clinics and specialists in hospitals is required.

methodsChronic hepatitis B (HBV) and C (HCV), NASH, and alcoholic steatohepatitis (ASH) patients who were assayed for Mac-2-binding protein glycosylation isomer (M2BPGi) (

resultsFIB-4 index >2, excluding HBV-infected patients, M2BPGi >0.5, ATX >0.5, and platelet count <20 × 10

conclusionsUsing appropriate markers and tools, we can establish a stepwise, practical, noninvasive, and etiology-based screening and follow-up system in primary and specialty care.

Indexed as

autotaxinfibrosis‐4 indexhepatocellular carcinomaMac‐2‐binding protein glycosylation isomermagnetic resonance elastography

Identifiers

PMID33102751
PMCPMC7578295
OpenAlexW3081101935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.