Evidence map›Paper›PMID 33102640›Full record

ArticleCurrent opinion in behavioral sciences2020

Using rodent models to understand interactions between gambling and substance use.

Barry Setlow, Shelby L Blaes, Matthew R Burns, R Joseph Dragone, Caitlin A Orsini

Abstract read
In one paragraph

Article in Current opinion in behavioral sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barry SetlowDepartment of Psychiatry, University of Florida, Gainesville, FL, 32610, USA.
Shelby L BlaesDepartment of Psychiatry, University of Florida, Gainesville, FL, 32610, USA.
Matthew R BurnsDepartment of Neurology, University of Florida, Gainesville, FL, 32610, USA.
R Joseph DragoneDepartment of Psychiatry, University of Florida, Gainesville, FL, 32610, USA.
Caitlin A OrsiniDepartment of Psychology, University of Texas at Austin, Austin, TX, 78712, USA.

Funding

Clinical and Translational Predoctoral training in Alzheimers Disease and Related DementiasT32AG061892 · NIA · UNIVERSITY OF FLORIDA · PI PARAMITA CHAKRABARTY, JADA M LEWIS · 2018 to 2026
$1.8M
Risk taking and cocaine use: interactions, mechanisms, and therapeutic targetsR01DA036534 · NIDA · UNIVERSITY OF FLORIDA · PI SETLOW, BARRY · 2015 to 2019
$1.7M
Neural circuits and mechanisms underlying maladaptive risk-taking following cocaine self-administrationR00DA041493 · NIDA · UNIVERSITY OF TEXAS AT AUSTIN · PI ORSINI, CAITLIN ANNE · 2019 to 2021
$745k
Neural circuits and mechanisms underlying maladaptive risk-taking following cocaine self-administrationK99DA041493 · NIDA · UNIVERSITY OF FLORIDA · PI ORSINI, CAITLIN ANNE · 2017 to 2018
$232k
NIA NIH HHS T32 AG061892NIDA NIH HHS K99 DA041493NIDA NIH HHS R00 DA041493NIDA NIH HHS R01 DA036534
6 · The paper itself

Abstract

Substance use is strongly associated with gambling, but the nature of this association can be difficult to determine. Rodents offer the opportunity to test causal models of these relationships through isolation of individual variables of interest. This review describes recent research in rodents showing: a) predisposing factors for both gambling-like behavior and substance use; b) exposure to drugs of abuse increasing gambling-like behavior; c) experience with gambling-like behavior increasing substance use; and d) links between gambling-like behavior and substance use in models of Parkinson's disease therapies. These findings reveal novel relationships between gambling and substance use, and highlight the utility of rodent models for future work in this area.

Indexed as

addictionGamblingratsrisk takingrodentssubstance use

Identifiers

PMID33102640
PMCPMC7583364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.