Evidence map›Paper›PMID 33102610›Full record

ArticleEye and vision (London, England)2020

A machine learning-based algorithm used to estimate the physiological elongation of ocular axial length in myopic children.

Tao Tang, Zekuan Yu, Qiong Xu, Zisu Peng, Yuzhuo Fan, Kai Wang, Qiushi Ren, Jia Qu, Mingwei Zhao

Abstract read
In one paragraph

Article in Eye and vision (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trend of Myopia Incidence Among Adolescents (2018-2025) in Senior High School: An 8-Year Retrospective Study in Multi-Regions of China, With Projections to 2030.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  2. Artificial intelligence in pediatric myopia - a narrative review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  3. Influence of Cycloplegia on Axial Length Prediction Models in a Paediatric Sample.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  4. Observational
  5. Article
  6. Axial elongation as a marker to identify obvious myopic shift in non-myopic eyes of Chinese children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  7. Article
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  9. IMI-Instrumentation for Myopia Management.Investigative ophthalmology & visual science · 2025
    Review
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  19. Insights into artificial intelligence in myopia management: from a data perspective.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  20. Panretinal Optical Coherence Tomography.IEEE transactions on medical imaging · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tao Tang *Department of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Beijing, 100044 China.
Zekuan Yu *Academy for Engineering & Technology, Fudan University, Shanghai, China.
Qiong XuDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Beijing, 100044 China.
Zisu PengDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Beijing, 100044 China.
Yuzhuo FanDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Beijing, 100044 China.
Kai WangDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Beijing, 100044 China.ORCID 0000-0002-4171-825X
Qiushi RenDepartment of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871 China.
Jia QuCollege of Optometry, Peking University Health Science Center, Beijing, China.
Mingwei ZhaoDepartment of Ophthalmology & Clinical Centre of Optometry, Peking University People's Hospital, Beijing, 100044 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAxial myopia is the most common type of myopia. However, due to the high incidence of myopia in Chinese children, few studies estimating the physiological elongation of the ocular axial length (AL), which does not cause myopia progression and differs from the non-physiological elongation of AL, have been conducted. The purpose of our study was to construct a machine learning (ML)-based model for estimating the physiological elongation of AL in a sample of Chinese school-aged myopic children.

methodsIn total, 1011 myopic children aged 6 to 18 years participated in this study. Cross-sectional datasets were used to optimize the ML algorithms. The input variables included age, sex, central corneal thickness (CCT), spherical equivalent refractive error (SER), mean K reading (K-mean), and white-to-white corneal diameter (WTW). The output variable was AL. A 5-fold cross-validation scheme was used to randomly divide all data into 5 groups, including 4 groups used as training data and one group used as validation data. Six types of ML algorithms were implemented in our models. The best-performing algorithm was applied to predict AL, and estimates of the physiological elongation of AL were obtained as the partial derivatives of

resultsAmong the six algorithms, the robust linear regression model was the best model for predicting AL, with a

conclusionsThe physiological elongation of the AL is rarely recorded in clinical data in China. In cases of unavailable clinical data, an ML algorithm could provide practitioners a reasonable model that can be used to estimate the physiological elongation of AL, which is especially useful when monitoring myopia progression in orthokeratology lens wearers.

Indexed as

Machine learningMyopiaMyopia progressionOcular axial lengthOrthokeratologyPhysiological elongation

Identifiers

PMID33102610
PMCPMC7579939

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.