Evidence map›Paper›PMID 33102544›Full record

ArticleFrontiers in veterinary science2020

Genetic Basis of Antigenic Variation of SAT3 Foot-And-Mouth Disease Viruses in Southern Africa.

Lorens Maake, William T Harvey, Lia Rotherham, Pamela Opperman, Jacques Theron, Richard Reeve, Francois F Maree

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lorens MaakeVaccine and Diagnostic Development Programme, Onderstepoort Veterinary Institute, Agricultural Research Council, Pretoria, South Africa.
William T HarveyBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Lia RotherhamVaccine and Diagnostic Development Programme, Onderstepoort Veterinary Institute, Agricultural Research Council, Pretoria, South Africa.
Pamela OppermanVaccine and Diagnostic Development Programme, Onderstepoort Veterinary Institute, Agricultural Research Council, Pretoria, South Africa.
Jacques TheronDepartment of Biochemistry, Genetics and Microbiology, Faculty of Agricultural and Natural Sciences, University of Pretoria, Pretoria, South Africa.
Richard ReeveBoyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
Francois F MareeVaccine and Diagnostic Development Programme, Onderstepoort Veterinary Institute, Agricultural Research Council, Pretoria, South Africa.
University of Pretoria · ZAGlasgow Centre for Population Health · GBOnderstepoort Veterinary Institute · ZA

Funding

Biotechnology and Biological Sciences Research Council BB/H009175/1Medical Research Council MR/R024758/1
6 · The paper itself

Abstract

Foot-and-mouth disease (FMD) continues to be a major burden for livestock owners in endemic countries and a continuous threat to FMD-free countries. The epidemiology and control of FMD in Africa is complicated by the presence of five clinically indistinguishable serotypes. Of these the Southern African Territories (SAT) type 3 has received limited attention, likely due to its restricted distribution and it being less frequently detected. We investigated the intratypic genetic variation of the complete P1 capsid-coding region of 22 SAT3 viruses and confirmed the geographical distribution of five of the six SAT3 topotypes. The antigenic cross-reactivity of 12 SAT3 viruses against reference antisera was assessed by performing virus neutralization assays and calculating the r

Indexed as

antigenicantigenic matchingcross-reactivityfoot-and-mouth disease (FMD)phylogenySouthern African Territory (SAT) type 3virus neutralization test

Identifiers

PMID33102544
PMCPMC7506032
OpenAlexW3080269373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.