Evidence map›Paper›PMID 33102442›Full record

ReviewFrontiers in chemistry2020

Extraction of Flavonoids From Natural Sources Using Modern Techniques.

Jaísa Oliveira Chaves, Mariana Corrêa de Souza, Laise Capelasso da Silva, Daniel Lachos-Perez, Paulo César Torres-Mayanga, Ana Paula da Fonseca Machado, Tânia Forster-Carneiro, Mercedes Vázquez-Espinosa, Ana Velasco González-de-Peredo, Gerardo Fernández Barbero and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed
33.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 556 citations in OpenAlex.

  1. Article
  2. Review
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  16. Date Palm Pollen (Molecules (Basel, Switzerland) · 2026
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  17. Article
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  20. Review

99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Jaísa Oliveira ChavesMultidisciplinary Laboratory in Food and Health, School of Applied Sciences, University of Campinas, Limeira, Brazil.
Mariana Corrêa de SouzaMultidisciplinary Laboratory in Food and Health, School of Applied Sciences, University of Campinas, Limeira, Brazil.
Laise Capelasso da SilvaMultidisciplinary Laboratory in Food and Health, School of Applied Sciences, University of Campinas, Limeira, Brazil.
Daniel Lachos-PerezLaboratory of Optimization, Design and Advanced Control - Bioenergy Research Program, School of Chemical Engineering, University of Campinas, Campinas, Brazil.
Paulo César Torres-MayangaSchool of Food Engineering, University of Campinas, Campinas, Brazil.
Ana Paula da Fonseca MachadoSchool of Food Engineering, University of Campinas, Campinas, Brazil.
Tânia Forster-CarneiroSchool of Food Engineering, University of Campinas, Campinas, Brazil.
Mercedes Vázquez-EspinosaDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Cadiz, Spain.
Ana Velasco González-de-PeredoDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Cadiz, Spain.
Gerardo Fernández BarberoDepartment of Analytical Chemistry, Faculty of Sciences, University of Cadiz, Cadiz, Spain.
Mauricio Ariel RostagnoMultidisciplinary Laboratory in Food and Health, School of Applied Sciences, University of Campinas, Limeira, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidad de Cádiz · ESUniversidad Nacional Micaela Bastidas de Apurimac · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids are one of the main groups of polyphenols found in natural products. Traditional flavonoid extraction techniques are being replaced by advanced techniques to reduce energy and solvent consumption, increase efficiency and selectivity, to meet increased market demand and environmental regulations. Advanced technologies, such as microwaves, ultrasound, pressurized liquids, supercritical fluids, and electric fields, are alternatives currently being used. These modern techniques are generally faster, more environmentally friendly, and with higher automation levels compared to conventional extraction techniques. This review will discuss the different methods available for flavonoid extraction from natural sources and the main parameters involved (temperature, solvent, sample quantity, extraction time, among others). Recent trends and their industrial importance are also discussed in detail, providing insight into their potential. Thus, this paper seeks to review the innovations of compound extraction techniques, presenting in each of them their advantages and disadvantages, trying to offer a broader scope in the understanding of flavonoid extraction from different plant matrices.

Indexed as

extractionflavonoidsmodern techniquesnatural productssample preparation

Identifiers

PMID33102442
PMCPMC7546908
OpenAlexW3088947129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.