Evidence map›Paper›PMID 33102417›Full record

ArticleFrontiers in public health2020

Coexistence of the Oxazolidinone Resistance-Associated Genes

Lara M Almeida, Anthony Gaca, Paulo M Bispo, François Lebreton, Jose T Saavedra, Rafael A Silva, Irinaldo D Basílio-Júnior, Felipe M Zorzi, Pedro H Filsner, Andrea M Moreno and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Methicillin-ResistantMicroorganisms · 2026
    Review
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  4. CRISPR-Cas systems in enterococci.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  5. Article
  6. Review
  7. Nasotracheal enterococcal carriage and resistomes: detection of optrA-, poxtA- and cfrD-carrying strains in migratory birds, livestock, pets, and in-contact humans in Spain.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  8. Ribosome-targeting antibiotics and resistanceRSC medicinal chemistry · 2023
    Review
  9. Article
  10. Article
  11. Vancomycin Resistance inMicroorganisms · 2022
    Review
  12. Review
  13. Article
  14. Evidence of Linezolid Resistance and Virulence Factors inAntibiotics (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Lara M AlmeidaInstitute of Pharmaceutical Sciences, Federal University of Alagoas, Maceió, Brazil.
Anthony GacaDepartment of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA, United States.
Paulo M BispoDepartment of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA, United States.
François LebretonDepartment of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA, United States.
Jose T SaavedraDepartment of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA, United States.
Rafael A SilvaInstitute of Pharmaceutical Sciences, Federal University of Alagoas, Maceió, Brazil.
Irinaldo D Basílio-JúniorInstitute of Pharmaceutical Sciences, Federal University of Alagoas, Maceió, Brazil.
Felipe M ZorziSchool of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
Pedro H FilsnerSchool of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
Andrea M MorenoSchool of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil.
Michael S GilmoreDepartment of Ophthalmology and Department of Microbiology, Harvard Medical School, Boston, MA, United States.
Harvard University · USUniversidade de São Paulo · BRUniversidade Federal de Alagoas · BR

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI Michael S Gilmore · 2009 to 2026
$39.4M
NIAID NIH HHS P01 AI083214
6 · The paper itself

Abstract

Oxazolidinones are one of the most important antimicrobials potentially active against glycopeptide- and β-lactam-resistant Gram-positive pathogens. Linezolid-the first oxazolidinone to be approved for clinical use in 2000 by the US Food and Drug Administration-and the newer molecule in the class, tedizolid, inhibit protein synthesis by suppressing the formation of the 70S ribosomal complex in bacteria. Over the past two decades, transferable oxazolidinone resistance genes, in particular

Indexed as

Enterococcus faeciumGram-Positive Bacterial InfectionsOxazolidinonesAnimalsBrazilDrug Resistance, BacterialEnterococcus faecalisSwineUnited StatesOxazolidinonescfr geneEnterococcus faecalislivestockoptrA geneoxazolidinonesresistance

Identifiers

PMID33102417
PMCPMC7546817
OpenAlexW3088401040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.