ArticleFrontiers in public health2020
SARS-CoV-2 Infections in the World: An Estimation of the Infected Population and a Measure of How Higher Detection Rates Save Lives.
Article in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Effects of behavioral intervention components to increase COVID-19 testing for African American/Black and Latine frontline essential workers not up-to-date on COVID-19 vaccination: Results of an optimization randomized controlled trial.Journal of behavioral medicine · 2025Trial
- Combatting SARS-CoV-2 With Digital Contact Tracing and Notification: Navigating Six Points of Failure.JMIR public health and surveillance · 2023Review
- Understanding the impact of digital contact tracing during the COVID-19 pandemic.PLOS digital health · 2022Article
- Effectiveness, Policy, and User Acceptance of COVID-19 Contact-Tracing Apps in the Post-COVID-19 Pandemic Era: Experience and Comparative Study.JMIR public health and surveillance · 2022Article
- Advanced Molecular and Immunological Diagnostic Methods to Detect SARS-CoV-2 Infection.Microorganisms · 2022Review
- Predictors of COVID-19 Fatality: A Worldwide Analysis of the Pandemic over Time and in Latin America.Journal of epidemiology and global health · 2022Article
- A Protective HLA Extended Haplotype Outweighs the Major COVID-19 Risk Factor Inherited From Neanderthals in the Sardinian Population.Frontiers in immunology · 2022Article
- COVID-19 mitigation by digital contact tracing and contact prevention (app-based social exposure warnings).Scientific reports · 2021Article
- Evaluation of the number of undiagnosed infected in an outbreak using source of infection measurements.Scientific reports · 2021Article
Corrections and comments
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1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper provides an estimation of the accumulated detection rates and the accumulated number of infected individuals by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Worldwide, on July 20, it has been estimated above 160 million individuals infected by SARS-CoV-2. Moreover, it is found that only about 1 out of 11 infected individuals are detected. In an information context in which population-based seroepidemiological studies are not frequently available, this study shows a parsimonious alternative to provide estimates of the number of SARS-CoV-2 infected individuals. By comparing our estimates with those provided by the population-based seroepidemiological ENE-COVID study in Spain, we confirm the utility of our approach. Then, using a cross-country regression, we investigated if differences in detection rates are associated with differences in the cumulative number of deaths. The hypothesis investigated in this study is that higher levels of detection of SARS-CoV-2 infections can reduce the risk exposure of the susceptible population with a relatively higher risk of death. Our results show that, on average, detecting 5 instead of 35 percent of the infections is associated with multiplying the number of deaths by a factor of about 6. Using this result, we estimated that 120 days after the pandemic outbreak, if the US would have tested with the same intensity as South Korea, about 85,000 out of their 126,000 reported deaths could have been avoided.
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