Evidence map›Paper›PMID 33102370›Full record

ArticleJournal of family medicine and primary care2020

Herbal medicine-induced multiple pulmonary pseudotumors.

Shin Takayama, Tetsuya Akaishi, Masakazu Hanagama, Yuko Itakura, Ryutaro Arita, Akiko Kikuchi, Tadashi Ishii

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of family medicine and primary care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shin TakayamaDepartment of Education and Support for Regional Medicine, Tohoku University School of Medicine, Sendai, Japan.
Tetsuya AkaishiDepartment of Education and Support for Regional Medicine, Tohoku University School of Medicine, Sendai, Japan.
Masakazu HanagamaDepartment of Respiratory Medicine, Red Cross Ishinimaki Hospital, Ishinomaki, Japan.
Yuko ItakuraDepartment of Pathology, Red Cross Ishinimaki Hospital, Ishinomaki, Japan.
Ryutaro AritaDepartment of Education and Support for Regional Medicine, Tohoku University School of Medicine, Sendai, Japan.
Akiko KikuchiDepartment of Education and Support for Regional Medicine, Tohoku University School of Medicine, Sendai, Japan.
Tadashi IshiiDepartment of Education and Support for Regional Medicine, Tohoku University School of Medicine, Sendai, Japan.
Tohoku University · JPIshinomaki Senshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Japanese herbal medicines (HMs) cause adverse drug reactions (ADRs); however, solid nodule formation is uncommon. In this report, we aimed to show that ADRs with HM can mimic lung cancer. A 63-year-old man complained of back pain. His physician prescribed a traditional Japanese HM, Keishikajutsubuto, which alleviated his symptoms. After 4 weeks, a chest radiograph showed multiple lung nodules that were absent 6 months earlier; the patient did not have cough, fever, or dyspnea. Computed tomography (CT) showed multiple, bilateral lung nodules; however, blood tests and lung biopsy showed no abnormalities, ruling out interstitial pneumonia and lung cancer. Three months after the HM was discontinued, CT showed resolution of the lesions. Interstitial pneumonia was reported as a side effect of HM; however, no such side effect was reported for Keishikajutsubuto. When a patient presents with multiple lung nodules, a side effect of HM should be considered as a differential diagnosis.

Indexed as

Adverse reactionherbal medicinelung nodulepseudotumor

Identifiers

PMID33102370
PMCPMC7567265
OpenAlexW3043866156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.