ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020
An Intelligent AIEgen with Nonmonotonic Multiresponses to Multistimuli.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Lipid-Targeting Multiresponsive Benzothiadiazole Fluorophore for Live-Cell Imaging and Real-Time Liver Injury Monitoring.Chemical & biomedical imaging · 2026Article
- Small Organic Molecule-Based Multicolor Fluorescent Smart Materials: From Design Principles and Optical Properties to Versatile Applications.ACS central science · 2026Review
- Molecular Descriptor of Electronic Transition for Regulating Polarity-Responsive Behavior of Heterocycle-Containing Probes.JACS Au · 2026Article
- Light-Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Wet Photolithography From Hydrogen Abstraction of a Quasi-Orthogonal Aggregation-Induced Emitter.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- An Acid-Responsive Fluorescent Molecule for Erasable Anti-Counterfeiting.Molecules (Basel, Switzerland) · 2024Article
- Article
- Regulating the proximity effect of heterocycle-containing AIEgens.Nature communications · 2023Article
- Natural Coumarin Isomers with Dramatically Different AIE Properties: Mechanism and Application.ACS central science · 2023Article
- Ratiometric Monitoring of Biogenic Amines by a Simple Ammonia-Response Aiegen.Foods (Basel, Switzerland) · 2022Article
- Mechanistic connotations of restriction of intramolecular motions (RIM).National science review · 2021Article
- Progress on Exploring the Luminescent Properties of Organic Molecular Aggregates by Multiscale Modeling.Frontiers in chemistry · 2021Review
- An Intelligent AIEgen with Nonmonotonic Multiresponses to Multistimuli.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intelligent stimulus-response (S/R) systems are the basis of natural process and machine control, which are intensively explored in biomimetic design and analytical/biological applications. However, nonmonotonic multi-S/R systems are still rarely studied so far. In this work, a rational design strategy is proposed to achieve such a unique S/R system by integrating opposite luminescence behaviors in one molecule. When solvent polarity increases, many heterocyclic or carbonyl-containing compounds often become more emissive due to the suppression of the proximity effect, whereas molecules with donor-acceptor (D-A) structures tend to be less emissive because of the twisted intramolecular charge transfer. Meanwhile, protonation on D/A moieties will weaken/strengthen the D-A interaction to result in blue/redshifted emissions. By combining a protonatable heterocyclic acceptor and a protonatable donor together in one molecule, nonmonotonic brightness responses to polarity stimuli and nonmonotonic color responses to pH stimuli can be achieved. The design strategy is successfully verified by a simple molecule named 4-(dimethylamino)styryl)quinoxalin-2(1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.