ArticleTranslational vision science & technology2020
Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics.
Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Cross-Device Field-of-View Scale Differences in Clinical OCT Angiography: Phantom Calibration and Large-Scale Clinical Validation.medRxiv : the preprint server for health sciences · 2026Article
- The Association of Retinal Capillary Density and Retinal Thickness in Diabetic Retinopathy.Investigative ophthalmology & visual science · 2025Article
- Unlocking the Potential of Vessel Density and the Foveal Avascular Zone in Optical Coherence Tomography Angiography as Biomarkers in Alzheimer's Disease.Healthcare (Basel, Switzerland) · 2024Review
- In Vivo Assessment of Retinal Phenotypes in Axenfeld-Rieger Syndrome.Investigative ophthalmology & visual science · 2024Article
- The Shape of the Foveal Avascular Zone: When a Circle Isn't Round.Translational vision science & technology · 2023Article
- Diurnal changes in choroidal optical coherence tomography angiography indices over 24 hours in healthy young adults.Scientific reports · 2023Article
- Racial differences in quantitative optical coherence tomography angiography findings between older non-diabetics with co-morbidities.PloS one · 2023Article
- Changes in Retinal Optical Coherence Tomography Angiography Indexes Over 24 Hours.Investigative ophthalmology & visual science · 2022Article
- Assessing Foveal Structure in Individuals withOphthalmology science · 2021Article
- Radial Peripapillary Capillary Plexus Sparing and Underlying Retinal Vascular Impairment in Intermediate Age-Related Macular Degeneration.Investigative ophthalmology & visual science · 2021Article
- OCTAVA: An open-source toolbox for quantitative analysis of optical coherence tomography angiography images.PloS one · 2021Article
- Early-stage macular telangiectasia type 2 vascular abnormalities are associated with interdigitation zone disruption.PloS one · 2021Article
- Retinal imaging biomarkers of Alzheimer's disease: A systematic review and meta-analysis of studies using brain amyloid beta status for case definition.Alzheimer's & dementia (Amsterdam, Netherlands)Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Purpose: The purpose of this study was to investigate the effect of device and scan size on quantitative optical coherence tomography angiography (OCT-A) metrics. Methods: The 3 × 3 mm scans from Optovue AngioVue and Zeiss AngioPlex systems were included for 18 eyes of 18 subjects without ocular pathology. The foveal avascular zone (FAZ) was segmented manually by two observers, from which estimates of FAZ area (using both the nominal image scale and the axial length corrected image scale) and acircularity were derived. Three scan sizes (3 mm, 6 mm HD, and 8 mm) from the AngioVue system were included for 15 eyes of 15 subjects without ocular pathology. For each subject, larger image sizes were resized to the same resolution as 3 × 3 mm scans, aligned, then cropped to a common area. FAZ area, FAZ acircularity, average and total parafoveal intercapillary area, vessel density, and vessel end points were computed. Results: Between the devices used here, there were no significant differences in FAZ acircularity ( Conclusions: The scan devices and sizes used here do not affect FAZ area measures derived from manual segmentations. In contrast, vessel morphometry metrics are affected by scan size. As individual differences in axial length induce differences in absolute scan size, extreme care should be taken when interpreting metrics of vessel morphometry, both between and within OCT-A devices. Translational Relevance: A better characterization of the confounds surrounding OCT-A retinal vasculature metrics can lead to improved application of these metrics as biomarkers for retinal and systemic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.