Evidence map›Paper›PMID 33101773›Full record

ArticleOncoimmunology2020

Cancer testis antigens in myelodysplastic syndromes revisited: a targeted RNA-seq approach.

Ana María Hurtado López, Tzu Hua Chen-Liang, María Zurdo, Salvador Carrillo-Tornel, Joaquín Panadero, Eduardo José Salido, Victor Beltrán, Begoña Muiña, MariLuz Amigo, Noelia Navarro-Villamor and 7 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Ana María Hurtado LópezHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.ORCID 0000-0002-3235-3690
Tzu Hua Chen-LiangHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
María ZurdoHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Salvador Carrillo-TornelHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Joaquín PanaderoGenomics Unit, Health Research Institute La Fe, Valencia, Spain.
Eduardo José SalidoDepartment of Hematology, Virgen De La Arrixaca University Hospital, Murcia, Spain.
Victor BeltránHematology Unit, H Virgen Del Castillo, Yecla, Spain.
Begoña MuiñaHematology Unit, Hospital Rafael Méndez, Lorca, Spain.
MariLuz AmigoHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Noelia Navarro-VillamorGenomics Unit, IMIB-Arrixaca, Murcia, Spain.
Rosa CifuentesHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Inés CalabriaGenomics Unit, Health Research Institute La Fe, Valencia, Spain.
Ana Isabel AntónGenomics Unit, IMIB-Arrixaca, Murcia, Spain.
Raúl TeruelHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Manuel MuroImmunology Department, Hospital Clínico Universitario Virgen De La Arrixaca, Murcia, Spain.ORCID 0000-0001-9987-0994
Vicente VicenteHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Andrés JerezHematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, IMIB, Murcia, Spain.
Hospital General Universitario Morales Meseguer · ESHospital Universitario Virgen de la Arrixaca · ESInstituto Murciano de Investigación Biosanitaria · ESHospital Rafael Méndez · ESHospital Virgen del Valle · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-Testis antigens (CTA) are named after the tissues where they are mainly expressed: in germinal and in cancer cells, a process that mimics many gametogenesis features. Mapping accurately the CTA gene expression signature in myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) is a prerequisite for downstream immune target-discovery projects. In this study, we take advantage of the use of azacitidine to treat high-risk MDS and CMML to draw the CTAs landscape, before and after treatment, using an

Indexed as

Myelodysplastic SyndromesNeoplasmsAntimetabolites, AntineoplasticAzacitidineHumansMaleSequence Analysis, RNATestisTranscription Factor DP1Antimetabolites, AntineoplasticAzacitidineTFDP3 protein, humanTranscription Factor DP1azacitidineCancer testis antigensmyelodysplastic syndromest-cell response

Identifiers

PMID33101773
PMCPMC7553508
OpenAlexW3089719338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.