ArticleBorderline personality disorder and emotion dysregulation2020
Altered interoception in patients with borderline personality disorder: a study using heartbeat-evoked potentials.
Article in Borderline personality disorder and emotion dysregulation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Heartbeat-Evoked Responses in M/EEG: A Systematic Review of Methods With Suggestions for Analysis and Reporting.Psychophysiology · 2026Pooled it
- Selective interoception impairments and treatment effects in borderline personality disorder.Translational psychiatry · 2026Article
- Transcutaneous auricular vagus nerve stimulation and emotional responding in borderline personality disorder: a randomized single-blind, sham-controlled study.Borderline personality disorder and emotion dysregulation · 2026Article
- Interoception and borderline personality disorder in female adolescents with restrictive eating disorders.Eating and weight disorders : EWD · 2026Article
- Heartbeat-evoked potentials reveal interoceptive dysfunction in clinical disorders: Experimental frameworks and promising applications.Psychological medicine · 2026Review
- Review of methods to derive the heartbeat-evoked potential: past practices and future directions.Social cognitive and affective neuroscience · 2026Review
- The heartbeat evoked potential and the prediction of functional seizure semiology.Brain communications · 2026Article
- Neurophysiological dynamics of visceral signals in emotion, self and bodily consciousness.Proceedings. Biological sciences · 2025Review
- Neural Interoceptive Processing Is Modulated by Deep Brain Stimulation to Subcallosal Cingulate Cortex for Treatment-Resistant Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Impaired interoception in Colombian victims of armed conflict with PTSD: a preliminary HEP study.Frontiers in psychology · 2025Article
- Exploring the Link Between Interoception and Symptom Severity in Premature Ventricular Contractions.Journal of clinical medicine · 2024Article
- Metabolic Dysfunctions, Dysregulation of the Autonomic Nervous System, and Echocardiographic Parameters in Borderline Personality Disorder: A Narrative Review.International journal of molecular sciences · 2024Review
- Heartbeat evoked potentials and autonomic arousal during dissociative seizures: insights from electrophysiology and neuroimaging.BMJ neurology open · 2024Article
- Beyond clinical observations: a scoping review of AI-detectable observable cues in borderline personality disorder.Frontiers in psychiatry · 2024Article
- The biosocial correlates and predictors of emotion dysregulation in autistic adults compared to borderline personality disorder and nonclinical controls.Molecular autism · 2023Article
- A predictive coding framework of allostatic-interoceptive overload in frontotemporal dementia.Trends in neurosciences · 2022Review
- Allostatic-Interoceptive Overload in Frontotemporal Dementia.Biological psychiatry · 2022Article
- Effects of 24-h acute total sleep deprivation on physiological coupling in healthy young adults.Frontiers in neuroscience · 2022Article
- Heartbeat-Evoked Cortical Potential during Sleep and Interoceptive Sensitivity: A Matter of Hypnotizability.Brain sciences · 2021Article
- Short-Term Fasting and Ingestion of Caloric Drinks Affect Heartbeat-Evoked Potentials and Autonomic Nervous System Activity in Males.Frontiers in neuroscience · 2021Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with borderline personality disorder (BPD) experience difficulties in emotional awareness (alexithymia), and often develop dissociative symptoms, which may reflect broader deficits in interoceptive awareness. Whether this is associated with alterations in cortical processing of interoception is currently unknown.
methodsWe utilized an electrophysiological marker of interoception, i.e. heartbeat-evoked potentials (HEP), and examined its relationship with electrocardiographic correlates of autonomic nervous system (ANS) functioning (heart rate variability), and with self-report measures of alexithymia, dissociation and borderline symptom severity in patients with BPD.
resultsIndividuals with BPD had higher HEP amplitudes over frontal electrodes compared to healthy controls. Sympathetic ANS activity was greater in BPD patients than in controls. Across groups, HEP amplitudes were associated with parasympathetic activity over central electrodes and correlated with alexithymia over frontal electrodes.
conclusionsThese findings support the idea that difficulties in emotional awareness in BPD are reflected in altered frontal electrophysiological markers of interception. Therefore, emotional awareness can be understood as failures of modulation between interoceptive and exteroceptive attention. Future research may aim to investigate whether altered interoception and its electrophysiological correlates are malleable by therapeutic intervention.
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