Evidence map›Paper›PMID 33101660›Full record

ReviewJournal of nutritional science2020

From lifespan to healthspan: the role of nutrition in healthy ageing.

Kremlin Wickramasinghe, John C Mathers, Suzan Wopereis, Daniel S Marsman, James C Griffiths

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nutritional science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Interventions that prolong multidimensional healthspan in humans: a systematic review of randomized controlled trials.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Kremlin WickramasingheWHO European Office for Prevention and Control of Noncommunicable Diseases (NCD Office), Moscow, Russian Federation.
John C MathersHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Suzan WopereisResearch Group Microbiology and Systems Biology, Netherlands Organization for Applied Scientific Research (TNO), Zeist, NL-3704 HE, The Netherlands.
Daniel S MarsmanGlobal Product Stewardship, P&G Health, Mason, OH 45040, USA.
James C GriffithsInternational and Scientific Affairs, Council for Responsible Nutrition-International, Washington, DC 20036, USA.
Netherlands Organisation for Applied Scientific Research · NLNewcastle University · GBPhysicians Committee for Responsible Medicine · USProcter & Gamble (United States) · USWHO European Office for the Prevention and Control of NCD · RU

Funding

Medical Research Council G0900686Medical Research Council MR/P020941/1
6 · The paper itself

Abstract

Across the globe, there has been a marked increase in longevity, but significant inequalities remain. These are exacerbated by inadequate access to proper nutrition and health care services and to reliable information to make the decisions related to nutrition and health care. Many in economically developing as well as developed societies are plagued with the double-burden of energy excess and undernutrition. This has resulted in mental and physical deterioration, increased non-communicable disease rates, lost productivity, increased medical costs and reduced quality of life. While adequate nutrition is fundamental to good health at all stages of the life course, the impact of diet on prolonging good quality of life during ageing remains unclear. For progress to continue, there is need for new and/or innovative approaches to promoting health as individuals age, as well as qualitative and quantitative biomarkers and other accepted tools that can measure improvements in physiological integrity throughout life. A framework for progress has been proposed by the World Health Organization in their Global Strategy and Action Plan on Ageing and Health. Here, we focused on the impact of nutrition within this framework, which takes a broad, person-centred emphasis on healthy ageing, stressing the need to better understand each individual's intrinsic capacity, their functional abilities at various life stages, and the impact of their mental, and physical health, as well as the environments they inhabit.

Indexed as

LongevityNutritional StatusHealthy AgingHumansNutritional RequirementsAgeingHealthspanLifespanLongevityNon-communicable diseasesNutritionPhenotypic flexibility

Identifiers

PMID33101660
PMCPMC7550962
OpenAlexW3081366394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.