Evidence map›Paper›PMID 33101591›Full record

ArticleOxidative medicine and cellular longevity2020

Protective Effect of Polydatin on Jejunal Mucosal Integrity, Redox Status, Inflammatory Response, and Mitochondrial Function in Intrauterine Growth-Retarded Weanling Piglets.

Hao Zhang, Yanan Chen, Yue Li, Tian Wang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

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  10. Experimental and therapeutic medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hao ZhangCollege of Animal Science & Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID https://orcid.org/0000-0002-1195-2475
Yanan ChenCollege of Animal Science & Technology, Nanjing Agricultural University, Nanjing 210095, China.
Yue LiInstitute of Animal Science, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Tian WangCollege of Animal Science & Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID https://orcid.org/0000-0002-9038-5009
Nanjing Agricultural University · CNJiangsu Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrauterine growth retardation (IUGR) delays the gut development of neonates, but effective treatment strategies are still limited. This study used newborn piglets as a model to evaluate the protective effect of polydatin (PD) against IUGR-induced intestinal injury. In total, 36 IUGR piglets and an equal number of normal birth weight (NBW) littermates were fed either a basal diet or a PD-supplemented diet from 21 to 35 days of age. Compared with NBW, IUGR induced jejunal damage and barrier dysfunction of piglets, as indicated by observable bacterial translocation, enhanced apoptosis, oxidative and immunological damage, and mitochondrial dysfunction. PD treatment decreased bacterial translocation and inhibited the IUGR-induced increases in circulating diamine oxidase activity (

Indexed as

Amine Oxidase (Copper-Containing)AMP-Activated Protein KinasesAnimalsDietary SupplementsDNA, MitochondrialEnergy MetabolismFetal Growth RetardationGlucosidesGlutathioneIntestinal MucosaJejunumLactic AcidMitochondriaProtective AgentsSignal TransductionSirtuin 1Amine Oxidase (Copper-Containing)AMP-Activated Protein KinasesDNA, MitochondrialGlucosidesGlutathioneLactic AcidpolydatinProtective AgentsSirtuin 1StilbenesSuperoxide DismutaseTumor Necrosis Factor-alpha

Identifiers

PMID33101591
PMCPMC7576365
OpenAlexW3092628114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.