Evidence map›Paper›PMID 33101484›Full record

ReviewExperimental and therapeutic medicine2020

COVID-19 and diabetes mellitus: Unraveling the hypotheses that worsen the prognosis (Review).

Radu Albulescu, Simona Olimpia Dima, Ioana Raluca Florea, Daniela Lixandru, Andreea Madalina Serban, Veronica Madalina Aspritoiu, Cristiana Tanase, Irinel Popescu, Sarah Ferber

Open access · diamondAbstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus.Frontiers in cardiovascular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Radu Albulescu'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Simona Olimpia Dima'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Ioana Raluca Florea'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Daniela LixandruFundeni Clinical Institute, 022328 Bucharest, Romania.
Andreea Madalina Serban'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Veronica Madalina Aspritoiu'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Cristiana Tanase'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Irinel Popescu'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Sarah Ferber'Nicolae Cajal' Institute, 'Titu Maiorescu' University, 004051 Bucharest, Romania.
Titu Maiorescu University · ROInstitutul Clinic Fundeni · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the caused disease - coronavirus disease 2019 (COVID-19), has affected so far >6,000,000 people worldwide, with variable grades of severity, and has already inflicted >350,000 deaths. SARS-CoV-2 infection seems severely affected by background diseases such as diabetes mellitus and its related complications, that seem to be favoring the most severe manifestations of SARS-CoV-2 and, therefore, require special attention in clinical care units. The present literature review focus on addressing several hypotheses explaining why diabetic patients could develop multi-organ failure in severe acute respiratory syndrome coronavirus (SARS-CoV) infections. Undoubtedly, as diabetes related complications are present it is expected to emphasize the severity of the COVID-19. Dermatological complications can occur and worsen in diabetic patients, and diseases such as acanthosis nigricans and psoriasis are prone to more severe manifestations of COVID-19. Approaches to treat SARS-CoV-2 infected patients, based on different solutions i.e. plasma therapy, use of antiviral compounds, development of vaccines or new therapeutic agents are ongoing.

Indexed as

angiotensin converting enzyme 2COVID-19diabetes mellitushypothesesSARS-CoV-2 infectionskin complications

Identifiers

PMID33101484
PMCPMC7579812
OpenAlexW3093695214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.