Evidence map›Paper›PMID 33101456›Full record

ArticleInfectious agents and cancer2020

IPSE, an abundant egg-secreted protein of the carcinogenic helminth

Evaristus C Mbanefo, Chinwike Terry Agbo, Yuanlong Zhao, Olivia K Lamanna, Kim H Thai, Shannon E Karinshak, Mohammad Afzal Khan, Chi-Ling Fu, Justin I Odegaard, Irina V Saltikova and 8 more

Open access · goldAbstract read
In one paragraph

Article in Infectious agents and cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. The cancer microbiome.Advances in clinical chemistry · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Extracellular vesicles of the liver flukeCurrent research in parasitology & vector-borne diseases · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Pathogens (Basel, Switzerland) · 2021
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 5 countries.

Evaristus C MbanefoDivision of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC 20010 USA.
Chinwike Terry AgboCarney Hospital, Boston, MA USA.
Yuanlong ZhaoMountainview Hospital, Las Vegas, NV USA.
Olivia K LamannaDivision of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC 20010 USA.
Kim H ThaiBaylor Scott and White Health, Temple, TX USA.
Shannon E KarinshakDepartment of Microbiology, Immunology, and Tropical Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC USA.
Mohammad Afzal KhanKing Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia.
Chi-Ling FuAbbvie, Sunnyvale, CA USA.
Justin I OdegaardGuardant Health, Redwood City, CA USA.
Irina V SaltikovaGuardant Health, Redwood City, CA USA.
Michael J SmoutJames Cook University, Townsville, Australia.
Luke F PenningtonDepartment of Structural Biology, Stanford University, Stanford, CA USA.
Mark R NicollsDivision of Pulmonology, Allergy, and Critical Care Medicine, Stanford University, Stanford, CA USA.
Theodore S JardetzkyDepartment of Structural Biology, Stanford University, Stanford, CA USA.
Alex LoukasJames Cook University, Townsville, Australia.
Paul J BrindleyDepartment of Microbiology, Immunology, and Tropical Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC USA.
Franco H FalconeInstitute of Parasitology, Justus-Liebig-Universität Gießen, Gießen, Germany.
Michael H HsiehDivision of Urology, Department of Surgery, Children's National Hospital, West Wing, 4th Floor, 111 Michigan Avenue NW, Washington, DC 20010 USA.ORCID 0000-0002-9650-2691
Children's National · USStanford University · USGeorge Washington University · USJames Cook University · AUAbbVie (United States) · USBaylor Scott & White Medical Center - Temple · USCarney Hospital · USGuardant (United States) · USJustus-Liebig-Universität Gießen · DEKing Faisal Specialist Hospital & Research Centre · SAnView Medical (United States) · USSiberian State Medical University · RU

Funding

Therapeutic Exploitation of IPSE, a Urogenital Parasite-Derived Host Modulatory Protein, for Bladder Hypersensitivity SyndromesR01DK113504 · NIDDK · CHILDREN'S RESEARCH INSTITUTE · PI HSIEH, MICHAEL HARRISON · 2017 to 2021
$2.4M
NIDDK NIH HHS R01 DK113504
6 · The paper itself

Abstract

backgroundSUMMARY:

Identifiers

PMID33101456
PMCPMC7578584
OpenAlexW3093771255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.