Evidence map›Paper›PMID 33101440›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2020

Traditional Herbal Medicine Candidates as Complementary Treatments for COVID-19: A Review of Their Mechanisms, Pros and Cons.

Rhea Veda Nugraha, Hastono Ridwansyah, Mohammad Ghozali, Astrid Feinisa Khairani, Nur Atik

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Computational evaluation ofCurrent research in structural biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Pidotimod in pediatrics: new evidence and future perspectives.Multidisciplinary respiratory medicine · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Herbal Self-medication Practice for Coronavirus Disease 2019 in Sudan: A Public Survey, 2021.Current therapeutic research, clinical and experimental · 2024
    Article
  12. Current therapeutic research, clinical and experimental · 2024
    Article
  13. AnFrontiers in pharmacology · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Phytochemicals ofMicroorganisms · 2023
    Review

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rhea Veda Nugraha *Graduate School of Biomedical Sciences Master Program, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.
Hastono Ridwansyah *Graduate School of Biomedical Sciences Master Program, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.
Mohammad GhozaliDepartment of Biomedical Sciences, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.
Astrid Feinisa KhairaniDepartment of Biomedical Sciences, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.
Nur AtikDepartment of Biomedical Sciences, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.ORCID https://orcid.org/0000-0001-5951-4733

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a new infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that belongs to the coronavirus family. The first case was reported in December 2019, and the disease has become a pandemic. Impaired immune regulation is one of the factors that play a role in its pathogenesis and results in poor outcomes of COVID-19 patients. There have been many studies with drug candidates used as antivirals or immunomodulators. However, the results of these investigations showed that the drug candidates were not significantly effective against the disease. Meanwhile, people believe that consuming herbal immunomodulators can prevent or even cure COVID-19. Unfortunately, specific preclinical and clinical trials to evaluate the effects of herbal immunoregulators have not been conducted. Certain natural compounds might be effective for the treatment of COVID-19 based on general concepts from previous experiments. This review discusses some herbal agents extracted from various plants, including

Identifiers

PMID33101440
PMCPMC7569437

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.