ArticleInternational journal of endocrinology2020
Vitamin D Deficiency as a Predictive Factor of Transient Hypocalcemia after Total Thyroidectomy.
Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Preoperative Calcium or Vitamin D Supplement in Thyroidectomy: A Systematic Review and Meta-Analysis.The Laryngoscope · 2025Pooled it
- Development and validation of risk prediction models for permanent hypocalcemia after total thyroidectomy in patients with papillary thyroid carcinoma.Scientific reports · 2025Article
- Article
- Review
- The effect of preoperative vitamin D values on hypocalcemia after total thyroidectomy.Turkish journal of surgery · 2024Article
- Investigating the Incidence and Risk Factors of Hypocalcemia After Laryngectomy.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Predictors of postoperative complications following thyroidectomy: A systematic review.Surgery in practice and science · 2024Review
- Preoperative Vitamin.D Status and Post-Total Thyroidectomy Hypocalcemia.Iranian journal of otorhinolaryngology · 2024Article
- Risk Factors for Calcium-Phosphate Disorders after Thyroid Surgery.Biomedicines · 2023Article
- Risk factors of postoperative hypoparathyroidism after total thyroidectomy in pediatric patients with thyroid cancer.Annals of pediatric endocrinology & metabolism · 2023Article
- Impact of thyroid cancer treatment on assisted reproductive technology outcomes in women with infertility.Journal of assisted reproduction and genetics · 2021Article
- Vitamin D Insufficiency Predicts Susceptibility of Parathyroid Hormone Reduction after Total Thyroidectomy in Thyroid Cancer Patients.International journal of endocrinology · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTotal thyroidectomy (TT) is recommended in the treatment of malignant and benignant thyroid diseases, and, to date, transient hypocalcemia is the most frequent complication after the procedure. We prospectively evaluated the role of vitamin D deficiency as a predictor of postoperative hypocalcemia.
methodsThis is a prospective cohort study which was conducted between January 2016 and April 2019. A total of 177 consecutive patients (141 (79.7%) women and 36 (20.3%) men) who underwent TT were included in the current study. Hypocalcemia occurred when serum calcium levels were below 8.0 mg/dL or 1.10 mmol/L. Patients were divided into two groups (Group 1, normocalcemic; Group 2, hypocalcemic) and were assessed taking into consideration preoperative serum 25-hydroxy vitamin D (25-OHD) levels, preoperative serum calcium levels, thyroid hormone levels, sex, body mass index (BMI), and smoking habits. Vitamin D deficiency was defined as 25-OHD levels <25 ng/mL.
resultsThe incidence of postoperative asymptomatic and symptomatic hypocalcemia in the two groups was 19.8% and 15.8%, respectively. Preoperative 25-OHD level was significantly different between Group 1 and Group 2 (31.5 ± 15.0 ng/mL vs 18.7 ± 9.8 ng/mL,
conclusionsPostoperative hypocalcemia is significantly associated with low preoperative levels of serum 25-OHD. Our studies demonstrate that vitamin D deficiency (<25 ng/mL) is an independent predictive factor of postoperative hypocalcemia.
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