Evidence map›Paper›PMID 33101293›Full record

ReviewFrontiers in immunology2020

Immunomodulatory Effects of Diterpenes and Their Derivatives Through NLRP3 Inflammasome Pathway: A Review.

Muhammad Torequl Islam, Sanaa K Bardaweel, Mohammad S Mubarak, Wojciech Koch, Katarzyna Gaweł-Beben, Beata Antosiewicz, Javad Sharifi-Rad

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Diterpenes: Nature's Hidden Gems of Immunomodulation.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Review
  11. Antimicrobial and Other Pharmacological Properties ofMolecules (Basel, Switzerland) · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Applications and Mechanisms of TripterygiumFrontiers in pharmacology · 2022
    Review
  18. Review
  19. Review
  20. NLRP3-Mediated Inflammation in Atherosclerosis and Associated Therapeutics.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Muhammad Torequl IslamLaboratory of Theoretical and Computational Biophysics, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Sanaa K BardaweelDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan.
Mohammad S MubarakDepartment of Chemistry, The University of Jordan, Amman, Jordan.
Wojciech KochChair and Department of Food and Nutrition, Medical University of Lublin, Lublin, Poland.
Katarzyna Gaweł-BebenDepartment of Cosmetology, University of Information Technology and Management in Rzeszów, Rzeszów, Poland.
Beata AntosiewiczDepartment of Cosmetology, University of Information Technology and Management in Rzeszów, Rzeszów, Poland.
Javad Sharifi-RadZabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, Iran.
University of Information Technology and Management in Rzeszow · PLUniversity of Jordan · JOMedical University of Lublin · PLTon Duc Thang University · VNZabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing protein (NLRP) inflammasomes are involved in the molecular pathogenesis of many diseases and disorders. Among NLRPs, the NLRP3 (in humans encoded by the

Indexed as

AnimalsDiterpenesHumansImmunomodulationInflammasomesInflammationMitochondriaNLR Family, Pyrin Domain-Containing 3 ProteinSignal TransductionDiterpenesInflammasomesNLR Family, Pyrin Domain-Containing 3 Proteinditerpenesinflammationmechanism of actionmitochondrial dysfunctionNLRP3

Identifiers

PMID33101293
PMCPMC7546345
OpenAlexW3087920412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.