ArticleFrontiers in psychiatry2020
Decreased Resting-State Interhemispheric Functional Connectivity in Medication-Free Obsessive-Compulsive Disorder.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring functional connectivity in large-scale brain networks in obsessive-compulsive disorder: a systematic review of EEG and fMRI studies.Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- Napping improves interhemispheric functional coordination during night shifts in nurses: analysis of voxel-mirrored homotopic connectivity.Frontiers in neurology · 2026Article
- Unveiling anomalies in visual processing regions in obsessive-compulsive disorder: evidence from gray matter volume and functional connectivity analyses.Brain imaging and behavior · 2025Article
- Dissecting Psychiatric Heterogeneity and Comorbidity with Core Region-Based Machine Learning.Neuroscience bulletin · 2023Review
- Associations between mother's depressive symptoms during pregnancy and newborn's brain functional connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Abnormal voxel-mirrored homotopic connectivity in first-episode major depressive disorder using fMRI: a machine learning approach.Frontiers in psychiatry · 2023Article
- Disrupted interhemispheric coordination of sensory-motor networks and insula in major depressive disorder.Frontiers in neuroscience · 2023Article
- Anatomical distance affects functional connectivity at rest in medicine-free obsessive-compulsive disorder.BMC psychiatry · 2022Article
- Disrupted resting-state interhemispheric functional connectivity in systemic lupus erythematosus patients with and without neuropsychiatric lupus.Neuroradiology · 2022Article
- Well-Being Is Associated With Local to Remote Cortical Connectivity.Frontiers in behavioral neuroscience · 2022Article
- Identification of chronic mild traumatic brain injury using resting state functional MRI and machine learning techniques.Frontiers in neuroscience · 2022Article
- Altered Static and Dynamic Interhemispheric Resting-State Functional Connectivity in Patients With Thyroid-Associated Ophthalmopathy.Frontiers in neuroscience · 2021Article
- Disrupted Asymmetry of Inter- and Intra-Hemispheric Functional Connectivity at Rest in Medication-Free Obsessive-Compulsive Disorder.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
16 authors.
Funding
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Abstract
objectiveDecreased homotopic connectivity of brain networks such as the cortico-striato-thalamo-cortical (CSTC) circuits may contribute to the pathophysiology of obsessive-compulsive disorder (OCD). However, little is known about interhemispheric functional connectivity (FC) at rest in OCD. In this study, the voxel-mirrored homotopic connectivity (VMHC) method was applied to explore interhemispheric coordination at rest in OCD.
methodsForty medication-free patients with OCD and 38 sex-, age-, and education level-matched healthy controls (HCs) underwent a resting-state functional magnetic resonance imaging. The VMHC and support vector machine (SVM) methods were used to analyze the data.
resultsPatients with OCD had remarkably decreased VMHC values in the orbitofrontal cortex, thalamus, middle occipital gyrus, and precentral and postcentral gyri compared with HCs. A combination of the VMHC values in the thalamus and postcentral gyrus could optimally distinguish patients with OCD from HCs.
conclusionsOur findings highlight the contribution of decreased interhemispheric FC within and outside the CSTC circuits in OCD and provide evidence to the pathophysiology of OCD.
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