Evidence map›Paper›PMID 33100973›Full record

ArticleFrontiers in cellular neuroscience2020

Synaptojanin2 Mutation Causes Progressive High-frequency Hearing Loss in Mice.

Elisa Martelletti, Neil J Ingham, Oliver Houston, Johanna C Pass, Jing Chen, Walter Marcotti, Karen P Steel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. A Systematic Review of Genes Affecting Endocochlear Potential.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Pooled it
  2. Pooled it
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  5. Investigating the effects of a cryptic splice site in the En2 splice acceptor sequence used in the IKMC knockout-first alleles.Mammalian genome : official journal of the International Mammalian Genome Society · 2024
    Article
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  9. The Effect of aCells · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elisa MartellettiWolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom.
Neil J InghamWolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom.
Oliver HoustonDepartment of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom.
Johanna C PassWolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom.
Jing ChenWolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom.
Walter MarcottiDepartment of Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom.
Karen P SteelWolfson Centre for Age-Related Diseases, King's College London, London, United Kingdom.
King's College London · GBUniversity of Sheffield · GB

Funding

Medical Research Council MR/N012119/1Wellcome Trust
6 · The paper itself

Abstract

Progressive hearing loss is very common in the human population but we know little about the underlying molecular mechanisms. Synaptojanin2 (

Indexed as

auditory functionexocytosishair cellsmouse mutantprogressive hearing losssingle hair cell recordingsynaptojanin2

Identifiers

PMID33100973
PMCPMC7546894
OpenAlexW3089113446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.