ArticleCardiopulmonary physical therapy journal2020
Cardiovascular disease risk is associated with middle cerebral artery blood flow velocity in older adults.
Article in Cardiopulmonary physical therapy journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Fat Consumption Attenuates Cortical Oxygenation during Mental Stress in Young Healthy Adults.Nutrients · 2023Trial
- Transcranial doppler assessment of preoperative cerebral blood flow velocity in cardiac surgery patients.Journal of clinical monitoring and computing · 2026Observational
- Longitudinal sex differences in cerebrovascular ageing in older adults: results from the brain in motion study.The Journal of physiology · 2026Article
- Association between cardiovascular disease risk, regional brain age gap, and cognition in healthy adults.Frontiers in aging neuroscience · 2025Article
- Cerebral Blood Flow in Alzheimer's Disease: A Meta-Analysis on Transcranial Doppler Investigations.Geriatrics (Basel, Switzerland) · 2024Review
- Lower middle cerebral artery blood velocity during low-volume high-intensity interval exercise in chronic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Effects of Physical Exercise on Cerebral Blood Velocity in Older Adults: A Systematic Review and Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2023Review
- Secondary Analysis of Walking Activities during the Acute Stroke Hospital Stay and Cerebrovascular Health.Cardiopulmonary physical therapy journal · 2022Article
- Cerebrovascular response to exercise interacts with individual genotype and amyloid-beta deposition to influence response inhibition with aging.Neurobiology of aging · 2022Article
- Sex Differences in Resilience and Resistance to Brain Pathology and Dysfunction Moderated by Cerebrovascular Response to Exercise and Genetic Risk for Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2022Article
- Effects of age and sex on middle cerebral artery blood velocity and flow pulsatility index across the adult lifespan.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Pilot Study to Characterize Middle Cerebral Artery Dynamic Response to an Acute Bout of Moderate Intensity Exercise at 3- and 6-Months Poststroke.Journal of the American Heart Association · 2021Article
- Chronic hyperglycemia before acute ischemic stroke impairs the bilateral cerebrovascular response to exercise during the subacute recovery period.Brain and behavior · 2021Article
- Self-Reported Omega-3 Supplement Use Moderates the Association between Age and Exercising Cerebral Blood Flow Velocity in Older Adults.Nutrients · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeThe aim of this study was to evaluate the
methodsWe recruited individuals who were cognitively normal older adults. CVD risk was assessed by the Pooled Cohort atherosclerotic cardiovascular disease (ASCVD) risk score. Transcranial Doppler ultrasound measured middle cerebral artery at rest and during a bout of moderate intensity exercise. We quantified white matter lesions from MRI and cognitive function outcomes included executive function, language, processing speed, and attention.
resultsSeventy-two participants 70.1 ± 4.7 years of age completed the study protocol. ASCVD risk score was significantly associated with resting and exercise MCAv (p<0.01) but not associated with white matter lesions (p>0.468). We observed a significant association between resting and exercise MCAv and language processing (p=0.010) but not other cognitive domains.
conclusionIn cognitively normal older adults, higher ASCVD risk score was associated with blunted resting and exercise MCAv and with lower language processing performance. These results highlight the need for CVD risk management to maintain optimal brain health.
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