ArticleClinical medicine insights. Circulatory, respiratory and pulmonary medicine2020
Diagnostic Role of Mean-Platelet Volume in Acute Pulmonary Embolism: A Meta-analysis and Systematic Review.
Article in Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Design-related bias in studies investigating diagnostic tests for venous thromboembolic diseases: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Association between mean platelet volume and pulmonary embolism: a systematic review and meta-analysis.Aging · 2021Pooled it
- Plateletcrit and Mean Platelet Volume in the Evaluation of Alcoholic Liver Cirrhosis and Nonalcoholic Fatty Liver Disease Patients.BioMed research international · 2021Trial
- Padua Score and D-dimer for Pulmonary Embolism Exclusion in the Elderly.Rambam Maimonides medical journal · 2025Article
- The Prognostic Value of Total Blood Count Parameter Ratios in Acute Pulmonary Embolism.Diagnostics (Basel, Switzerland) · 2024Article
- Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment.Biomedicines · 2024Review
- Acute Pulmonary Embolism in Oman: A Situational Analysis.Oman medical journal · 2023Article
- Mean platelet volume as an effective biomarker for predicting high-risk patients of hereditary thrombophilia: A retrospective study.Northern clinics of Istanbul · 2023Article
- The Predictive Value of Cell Blood Count Parameters to Diagnose Pulmonary Embolism in Patients with SARS-CoV-2 Infection: A Case Control Study.Antibiotics (Basel, Switzerland) · 2022Article
- Plasma brain natriuretic peptide, platelet parameters, and cardiopulmonary function in chronic obstructive pulmonary disease.World journal of clinical cases · 2021Article
- Predictive Value of MPV and Plasma NT-ProBNP Combined with the Simplified Geneva Scale for the Prognosis of Acute Pulmonary Embolism.Evidence-based complementary and alternative medicine : eCAM · 2021Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute pulmonary embolism (PE) is the third most fatal cardiovascular disease. PE is frequently misdiagnosed due to its clinical presentation's heterogeneity and the inexistence of biomarkers for its immediate diagnosis. Mean platelet volume (MPV) has shown a potential role as a biomarker in acute PE. In this analysis, we aimed to systematically compare the MPV in patients with and without definite diagnosis of PE, in emergency departments.
methodsEmbase, PubMed and Medline were searched for relevant publications, in English. The main inclusion criteria were studies which compared MPV in patients with acute PEA versus a control group.
resultsThirteen studies consisting of a total number of 2428 participants were included. Of the participants included, 1316 were patients with confirmed acute PE, and 1112 were assigned to the control group. MPV was significantly higher in patients with acute PE than in controls (RR: 0.84, 95% CI: 0.76 - 0.92;
conclusionsThis analysis showed higher MPV to be associated with acute PE immediate diagnosis. These data show promise for the use of MPV as a readily available biomarker for the diagnosis of acute PE at the emergency department.
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