Evidence map›Paper›PMID 33100802›Full record

ReviewThe International journal of angiology : official publication of the International College of Angiology, Inc2020

Acute Lower Limb Ischemia-Etiology, Pathology, and Management.

Balaji Natarajan, Prashant Patel, Ashis Mukherjee

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The International journal of angiology : official publication of the International College of Angiology, Inc, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06693427 (Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06693427 completednot on this mapstarted 2021, after this paper: background citation

Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation

TypeobservationalSponsorDIMITRIOS KATSAROSRan2021 to 2023Enrolled72ConditionsPhantom Limb Pain, Amputation, Anesthesia, LocalArmsPeripheral Nerve Block
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. CT Angiography of the Upper Extremities: Review of Acute Arterial Entities.Radiographics : a review publication of the Radiological Society of North America, Inc · 2025
    Review
  15. Article
  16. Article
  17. Femoro-popliteal endovascular interventions.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Balaji NatarajanDepartment of Cardiology, University of California Riverside, School of Medicine, Riverside, California.
Prashant PatelDepartment of Cardiology, University of California Riverside, School of Medicine, Riverside, California.
Ashis MukherjeeDepartment of Cardiology, University of California Riverside, School of Medicine, Riverside, California.
University of California, Riverside · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute limb ischemia (ALI) is a vascular emergency associated with a high risk for limb loss and death. Most cases result from in situ thrombosis in patients with preexisting peripheral arterial disease or those who have undergone vascular procedures including stenting and bypass grafts. The other common source is cardioembolic. The incidence has decreased in recent times due to better anticoagulation strategies. Patients with suspected ALI should be evaluated promptly by a vascular specialist and consideration should be given for transfer to a higher level of care if such expertise is not available locally. Initial assessment should focus on staging severity of ischemic injury and potential for limb salvage. Neurological deficits can occur early and are an important poor prognostic sign. Duplex ultrasound and computed tomography angiography help plan intervention in patients with a still-viable limb and prompt catheter-based angiography is mandated in patients with an immediately threatened limb. Further investigations need to be pursued to differentiate embolic from thrombotic cause for acute occlusion as this can change management. Options include intravascular interventions, surgical bypass, or a hybrid approach. In this article, the authors discuss the common etiologies, clinical evaluation, and management of patients presenting with acute limb ischemia.

Indexed as

acute limb ischemiaamputation.etiologylimb viabilitythrombectomythromboembolismthrombolysis

Identifiers

PMID33100802
PMCPMC7577793
OpenAlexW3037652044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.