Evidence map›Paper›PMID 33100792›Full record

ArticleJournal of pharmacy & bioallied sciences

Inhibition of pancreatic elastase

Yesi Desmiaty, Esti Mulatsari, Fadlina Chany Saputri, Muhammad Hanafi, Rini Prastiwi, Berna Elya

Open access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Food science and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yesi DesmiatyDepartment of Phytochemistry, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia.
Esti MulatsariDepartment of Phytochemistry, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia.
Fadlina Chany SaputriDepartment of Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Muhammad HanafiDepartment of Phytochemistry, Faculty of Pharmacy, Pancasila University, Jakarta, Indonesia.
Rini PrastiwiDepartment of Pharmacognosy, Faculty of Pharmacy, Universitas Muhammadiyah Prof. Dr. Hamka, Jakarta, Indonesia.
Berna ElyaDepartment of Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Pancasila University · IDUniversity of Indonesia · IDUniversitas Muhammadiyah Prof Dr Hamka · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveElastases are protease enzymes, which mainly hydrolyze proteins of the connective tissue, so they have a significant impact on human disease.

methodDried leaves powder of

resultThe methanol extract showed significantly inhibited elastase with IC50 186.13 μg/mL, but ethyl acetate extract showed weak activity, and

conclusionThis research has opened new insights into understanding that constituents of

Indexed as

Docking studieselastase inhibitorellagic acidRubus rosifolius

Identifiers

PMID33100792
PMCPMC7574744
OpenAlexW3044061171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.