Evidence map›Paper›PMID 33100749›Full record

ArticleUrology annals

Epidemiology of parvovirus B19 and anemia among kidney transplant recipients: A meta-analysis.

Charat Thongprayoon, Nadeen J Khoury, Tarun Bathini, Narothama Reddy Aeddula, Boonphiphop Boonpheng, Ploypin Lertjitbanjong, Kanramon Watthanasuntorn, Napat Leeaphorn, Supavit Chesdachai, Aldo Torres-Ortiz and 4 more

Open access · goldAbstract read
In one paragraph

Article in Urology annals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Navigating Anemia Therapy in CKD With Hypoxia-Inducible Factor Activators: A Review.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Charat ThongprayoonDepartment of Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, USA.
Nadeen J KhouryDepartment of Medicine, Division of Nephrology, Henry Ford Hospital, Detroit, Michigan, USA.
Tarun BathiniDepartment of Internal Medicine, University of Arizona, Tucson, Arizona, USA.
Narothama Reddy AeddulaDepartment of Medicine, Division of Nephrology, Indiana University School of Medicine and Deaconess Health System, Evansville, Indiana, USA.
Boonphiphop BoonphengDepartment of Internal Medicine, East Tennessee State University, Johnson City, Tennessee, USA.
Ploypin LertjitbanjongDepartment of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA.
Kanramon WatthanasuntornDepartment of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA.
Napat LeeaphornDepartment of Medicine, Renal Transplant Program, University of Missouri-Kansas City School of Medicine, Saint Luke's Health System, Kansas City, Missouri, USA.
Supavit ChesdachaiDepartment of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.
Aldo Torres-OrtizDepartment of Medicine, Division of Nephrology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Wisit KaewputDepartment of Military and Community Medicine, Phramongkutklao College of Medicine, Mahidol University, Bangkok, Thailand.
Jackrapong BruminhentDepartment of Medicine, Division of Infectious Diseases, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Michael A MaoDepartment of Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Wisit CheungpasitpornDepartment of Medicine, Division of Nephrology, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Mayo Clinic · USEast Tennessee State University · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersistent anemia has been described in kidney transplant (KTx) recipients with parvovirus B19 virus infection. However, the epidemiology of parvovirus B19 and parvovirus B19-related anemia after KTx remains unclear. We conducted this systematic review (1) to investigate the incidence of parvovirus B19 infection after KTx and (2) to assess the incidence of parvovirus B19 among KTx patients with anemia. MATERIALS AND

methodsA systematic review was conducted in EMBASE, MEDLINE, and Cochrane databases from inception to March 2019 to identify studies that reported the incidence rate of parvovirus B19 infection and/or seroprevalence of parvovirus B19 in KTx recipients. Effect estimates from the individual studies were extracted and combined using random-effects, generic inverse variance method of DerSimonian and Laird. The protocol for this systematic review is registered with PROSPERO (no. CRD42019125716).

resultsNineteen observational studies with a total of 2108 KTx patients were enrolled. Overall, the pooled estimated seroprevalence of parvovirus B19 immunoglobulin G was 62.2% (95% confidence interval [CI]: 45.8%-76.1%). The pooled estimated incidence rate of positive parvovirus B19 DNA in the 1

conclusionThe overall estimated incidence of positive parvovirus B19 DNA after KTX is 10.3%. Among KTx with anemia, the incidence rate of positive parvovirus B19 DNA is 27.4%. The incidence of positive parvovirus B19 DNA does not seem to decrease overtime.

Indexed as

Kidney transplantationmeta-analysisparvovirus B19renal transplantationsystematic reviews

Identifiers

PMID33100749
PMCPMC7546070
OpenAlexW3035527927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.