ArticleThe Indian journal of radiology & imaging
A unique presentation of 5-fluorouracil (5-FU) induced cerebral encephalopathy.
Article in The Indian journal of radiology & imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- 5-Fluorouracil-Induced Acute Toxic Leukoencephalopathy: A Rare Adverse Effect and Its Early Detection on MRI.Cureus · 2025Article
- Brain-heart: first case report of simultaneous toxicity of 5-fluorouracil.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Article
- Recurrent Reversible Stroke-Like Encephalopathy After 5-Fluorouracil (5-FU) Chemotherapy: A Case Report and Literature Review.The American journal of case reports · 2023Review
- Transient Coma and Signs of Encephalopathy Related to 5-Fluorouracil and Carboplatin: A Case Report.Case reports in oncologyArticle
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
5-Fluorouracil (5-FU), a commonly used antimetabolite and antineoplastic agent, has been approved for the treatment of various cancers. It is associated with systemic side-effects such as gastrointestinal problems, neutropenia. 5-FU-related encephalopathy is very rarely reported. Imaging with computed tomography (CT) and magnetic resonance imaging (MRI) plays a key role in diagnosing and monitoring the changes. Since the prognosis of cerebral involvement is usually good if recognized and treated in time, the reporting radiologist and treating physician should be familiar with them. We present a rare case of 5-FU-induced encephalopathy that was diagnosed based on her clinical and MRI findings and managed successfully.
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