ArticleProceedings (Baylor University. Medical Center)2020
The BRASH syndrome, a synergistic arrhythmia phenomenon.
Article in Proceedings (Baylor University. Medical Center), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- From Salvador Dali and Von Gogh to BRASH: a case-based systematic literature review of digoxin induced BRASH syndrome.Future cardiology · 2025Pooled it
- Failure of Implantable Cardioverter-defibrillator Pacing Capture in BRASH Syndrome with Severe Hyperkalemia.The Journal of innovations in cardiac rhythm management · 2026Article
- Review
- Article
- BRASH syndrome: a systematic review of clinical manifestations and associated risk factors.World journal of emergency medicine · 2025Article
- Critical presentation of bradycardia, renal failure, atrioventricular nodal blockade, shock, and hyperkalemia syndrome: A case report.World journal of clinical cases · 2025Article
- Article
- Unusual electrocardiographic presentation associated with severe hyperkalemia.European heart journal. Case reports · 2023Article
- Article
- Article
- BRASH Syndrome Presenting With Idioventricular Escape Rhythm in a Patient With Trifascicular Block.Cureus · 2022Article
- Article
- Two Cases of BRASH Syndrome: A Diagnostic Challenge.European journal of case reports in internal medicine · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BRASH syndrome is a relatively novel clinical entity with profound bradycardia secondary to simultaneous metabolic derangement and drug toxicity. The syndrome is a clinical pentad of bradycardia, acute kidney injury, use of atrioventricular nodal blocking agents, shock, and hyperkalemia. It is widely underrecognized with selectively few reports, mainly in the elderly population. We present a 43-year-old woman on two oral atrioventricular blocking agents who presented with 1 week of increasing lethargy with rapid deterioration into cardiac arrest with subsequent shock postresuscitation. She was found to have hyperkalemia, metabolic acidosis, and acute kidney injury on arrival. Her initial electrocardiogram was remarkable for sinus arrest and junctional bradycardia. She was treated with a temporary pacemaker, renal replacement therapy, and potassium-lowering agents, with subsequent improvement resulting in conversion to normal sinus rhythm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.