ArticleProceedings (Baylor University. Medical Center)2020
Adult Langerhans cell histiocytosis of the central nervous system.
Article in Proceedings (Baylor University. Medical Center), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Monocytic meningitis complicating histiocytosis and response to MEK-inhibitor: a case series.Annals of hematology · 2025Article
- Adult-onset Langerhans cell histiocytosis with multisystem involvement: A rare case report.Radiology case reports · 2025Article
- Unusual Long-Term Survival in an Adult Patient With Langerhans Cell Histiocytosis and Central Nervous System Involvement: A Case Report.Case reports in hematology · 2025Article
- Comparison of neuroimaging features of histiocytic neoplasms with central nervous system involvement: a retrospective study of 121 adult patients.European radiology · 2023Article
- Histiocytic Disorder Mimicking a Brain Tumor: A Report of 2 Rare Cases.The American journal of case reports · 2022Article
- Langerhans Cell Histiocytosis Manifests with Acute Severe Hypernatremia during Hospitalization.Case reports in nephrology · 2022Article
- Survivorship Issues in Adult Patients With Histiocytic Neoplasms.Journal of the National Comprehensive Cancer Network : JNCCN · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Langerhans cell histiocytosis (LCH), a disorder characterized by aberrant function and proliferation of mononuclear phagocytic cells called Langerhans cells, usually occurs in those <15 years of age. Adult-onset LCH is extremely rare. We present a case of a 35-year-old woman who presented with multiple episodes of confusion, rapidly progressive cognitive decline, and multiple endocrinopathies, including diabetes insipidus. Brain imaging showed a hypothalamic lesion, and biopsy results confirmed the diagnosis of LCH. Given the wide variety of presentations and the multiple differential diagnoses of hypothalamic lesions, it is essential to be aware of this uncommon condition, especially in adults, where it may be underdiagnosed.
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