Evidence map›Paper›PMID 33100380›Full record

ArticleJournal of molecular structure2021

Identification of alkaloids from

Rajesh Ghosh, Ayon Chakraborty, Ashis Biswas, Snehasis Chowdhuri

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular structure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Antiviral Activity of Natural Herbs and their Isolated BioactiveCompounds: A Review.Combinatorial chemistry & high throughput screening · 2024
    Review
  6. Chemical Characterization of Different Extracts ofAntioxidants (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Identification of Alkaloids fromChemistrySelect · 2022
    Article
  16. Article
  17. Review
  18. Potential of Natural Alkaloids From Jadwar (Frontiers in molecular biosciences · 2022
    Article
  19. Novel Drug Design for Treatment of COVID-19: A Systematic Review of Preclinical Studies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Review
  20. Ayurveda Rasayana as antivirals and immunomodulators: potential applications in COVID-19.Environmental science and pollution research international · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rajesh GhoshSchool of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar, India.
Ayon ChakrabortySchool of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar, India.
Ashis BiswasSchool of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar, India.
Snehasis ChowdhuriSchool of Basic Sciences, Indian Institute of Technology Bhubaneswar, Bhubaneswar, India.
Indian Institute of Technology Bhubaneswar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic, caused by SARS CoV-2, is responsible for millions of death worldwide. No approved/proper therapeutics is currently available which can effectively combat this outbreak. Several attempts have been undertaken in the search of effective drugs to control the spread of SARS CoV-2 infection. The main protease (Mpro), key component for the cleavage of the viral polyprotein, is considered to be one of the important drug targets for treating COVID-19. Various phytochemicals, including polyphenols and alkaloids, have been proposed as potent inhibitors of Mpro. The alkaloids from leaf extracts of

Indexed as

COVID-19COVID-19, corona virus disease 2019Docking and molecular dynamics simulationMD, molecular dynamicsMpro, main proteaseRg, radius of gyrationRMSD, root mean square deviationRMSF, root mean square fluctuationSARS CoV-2 main proteaseSARS CoV-2, severe acute respiratory syndrome corona virus-2SASA, solvent accessible surface areaVasaka Alkaloids

Identifiers

PMID33100380
PMCPMC7571971
OpenAlexW3092990052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.