Evidence map›Paper›PMID 33100227›Full record

SynthesisSystematic reviews2020

Effects of oncological care pathways in primary and secondary care on patient, professional and health systems outcomes: a systematic review and meta-analysis.

Jolanda C van Hoeve, Robin W M Vernooij, Michelle Fiander, Peter Nieboer, Sabine Siesling, Thomas Rotter

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05845632 unknown statusnot on this mapstarted 2022, after this paper: background citation

Association Between Time to Treatment and Disease-free Survival of Patients With High-risk Cutaneous Squamous Cell Carcinoma in the Head and Neck Region.

TypeobservationalSponsorMaastricht University Medical CenterRan2022 to 2023Enrolled965ConditionsCarcinoma, Squamous Cell, Skin Cancer, Carcinoma, Squamous Cell, Skin, Carcinoma, Squamous Cell of Head and NeckArmsTreatment
NCT06046625 active not recruitingnot on this mapstarted 2021, after this paper: background citation

The Needs and Preferences of Patients With High-risk Cutaneous Squamous Cell Carcinomas in the Head Neck Region: a Qualitative Approach

TypeobservationalSponsorMaastricht University Medical CenterRan2021 to 2025Enrolled15ConditionsCutaneous Squamous Cell Carcinoma, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Squamous Cell Carcinoma, Squamous Cell Carcinoma of Head and NeckArmsRegular care with additional administration of a semi-structured interview
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Mapping integrated care for brain tumour-related epilepsy in the Italian RIN-IRCCS network.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  4. Review
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  11. "I Became the Messenger Between the Hospitals": A Study on the Journeys of People With Cancer Using the Critical Incident Technique.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  12. Visual Modeling Languages in Patient Pathways: Scoping Review.Interactive journal of medical research · 2024
    Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jolanda C van HoeveDepartment Health Technology & Services Research, University of Twente, Enschede, the Netherlands. j.c.vanhoeve@utwente.nl.
Robin W M VernooijDepartment of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Michelle FianderCollege of Pharmacy, Department of Pharmacology, University of Utah, Salt Lake City, USA.
Peter NieboerWilhelmina Hospital, Assen, the Netherlands.
Sabine SieslingDepartment Health Technology & Services Research, University of Twente, Enschede, the Netherlands.
Thomas RotterSchool of Nursing, Queen's University, Kingston, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPathways are frequently used to improve care for cancer patients. However, there is little evidence about the effects of pathways used in oncological care. Therefore, we performed a systematic review and meta-analysis aiming to identify and synthesize existing literature on the effects of pathways in oncological care.

methodsAll patients diagnosed with cancer in primary and secondary/tertiary care whose treatment can be characterized as the strategy "care pathways" are included in this review. A systematic search in seven databases was conducted to gather evidence. Studies were screened by two independent reviewers. Study outcomes regarding patients, professionals, and system level were extracted from each study.

resultsOut of 13,847 search results, we selected 158 articles eligible for full text assessment. One hundred fifty studies were excluded and the remaining eight studies represented 4786 patients. Most studies were conducted in secondary/tertiary care. Length of stay (LOS) was the most common used indicator, and was reported in five studies. Meta-analysis based on subgroups showed an overall shorter LOS regarding gastric cancer (weighted mean difference (WMD)): - 2.75, CI: - 4.67 to - 0.83) and gynecological cancer (WMD: - 1.58, CI: - 2.10 to - 1.05). Costs were reported in six studies and most studies reported lower costs for pathway groups.

conclusionsDespite the differences between the included studies, we were able to present an evidence base for cancer care pathways performed in secondary/tertiary care regarding the positive effects of LOS in favor of cancer care pathways. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42017057592.

Indexed as

NeoplasmsSecondary Health CareDelivery of Health CareHumansLength of StayMedical OncologyCancerCare mapsCare pathwaysClinical pathwaysIntegrated care pathwaysOncologySystematic review

Identifiers

PMID33100227
PMCPMC7586678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.