Evidence map›Paper›PMID 33100134›Full record

ArticleJournal of the American Heart Association2020

Association of Exhaled Carbon Monoxide With Ideal Cardiovascular Health, Circulating Biomarkers, and Incidence of Heart Failure in the Framingham Offspring Study.

Bradley Tun, Rachel Ehrbar, Meghan Short, Susan Cheng, Ramachandran S Vasan, Vanessa Xanthakis

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Bradley TunDepartment of Medicine Boston University School of Medicine and Boston Medical Center Boston MA.
Rachel EhrbarDepartment of Biostatistics Boston University School of Public Health Boston MA.
Meghan ShortGlenn Biggs Institute for Alzheimer's Disease & Neurodegenerative Diseases University of Texas Health Sciences Center San Antonio TX.
Susan ChengSmidt Heart Institute Cedars-Sinai Medical Center Los Angeles CA.
Ramachandran S VasanNational Heart, Blood and Lung Institute Framingham Heart Study Framingham MA.
Vanessa XanthakisDepartment of Biostatistics Boston University School of Public Health Boston MA.
Boston University · USCedars-Sinai Medical Center · USThe University of Texas Health Science Center at San Antonio · US

Funding

FRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · 2019 to 2024
$29.8M
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS HHSN268201500001INHLBI NIH HHS N01 HC025195
6 · The paper itself

Abstract

Background Exhaled carbon monoxide (eCO) is directly associated with traditional cardiovascular disease risk factors and incident cardiovascular disease. However, its relation with the cardiovascular health score and incidence of heart failure (HF) has not been investigated. Methods and Results We measured eCO in 3521 Framingham Heart Study Offspring participants attending examination cycle 6 (mean age 59 years, 53% women). We related the cardiovascular health score (composite of blood pressure, fasting plasma glucose, total cholesterol, body mass index, smoking, diet, and physical activity) to eCO adjusting for age, sex, and smoking. Higher cardiovascular health scores were associated with lower eCO (β=-0.02,

Indexed as

AgedBiomarkersBlood PressureCarbon MonoxideExhalationFemaleHealth StatusHeart FailureHumansIncidenceLongitudinal StudiesMaleMiddle AgedStroke VolumeSurvival RateBiomarkersCarbon Monoxidecarbon monoxidecardiac biomarkerscardiovascular healthheart failure

Identifiers

PMID33100134
PMCPMC7763395
OpenAlexW3093648147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.