ArticleJournal of diabetes science and technology2022
HbA1c Is Disproportionately Higher in Women and Older People With Type 1 Diabetes Compared With Flash Glucose Monitoring Metrics of Glycemic Control.
Article in Journal of diabetes science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- CGM-derived average glucose is more strongly associated with microvascular complications than HbA1c in type 1 diabetes.Diabetes, obesity & metabolism · 2026Observational
- Persistent C-peptide secretion is associated with favourable CGM metrics in adults with type 1 diabetes.Diabetologia · 2026Article
- Associations of Hemoglobin Glycation Index with Glucose Variability and Time in Ranges in Patients with Type 2 Diabetes Undergoing Continuous Glucose Monitoring.International journal of medical sciences · 2026Article
- Potential Molecular Biomarkers for Predicting and Monitoring Complications in Type 2 Diabetes Mellitus.Molecules (Basel, Switzerland) · 2025Review
- "Insights into HbA1c: Key Role in Diabetes Screening and Associated Conditions" - A Comprehensive Review.Journal of pharmacy & bioallied sciences · 2025Review
- Association between the GMI/HbA1c ratio and preclinical carotid atherosclerosis in type 1 diabetes: impact of the fast-glycator phenotype across age groups.Cardiovascular diabetology · 2025Article
- Factors associated with hemoglobin glycation index in adults with type 1 diabetes mellitus: The FGM-Japan study.Journal of diabetes investigation · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsDiscrepancy between HbA1c and glucose exposure may have significant clinical implications. We sought to assess predictors of disparity between HbA1c and flash monitoring metrics and how these relate to microvascular complications.
methodsWe conducted a cross-sectional study of adults with type 1 diabetes (
resultsActual HbA1c and estimated HbA1c were strongly correlated (
conclusionsHbA1c appears to overestimate glucose exposure in women and older people with type 1 diabetes. This has potentially important clinical implications, as is hinted at by the independent relationship with retinopathy prevalence. It may also be of relevance when considering the use of HbA1c for the diagnosis of diabetes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.