Evidence map›Paper›PMID 33099999›Full record

ArticleThe Journal of organic chemistry2020

Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils.

Dan E Adolfsson, Mohit Tyagi, Pardeep Singh, Adrian Deuschmann, Jörgen Ådén, Anna L Gharibyan, Sanduni Wasana Jayaweera, Anders E G Lindgren, Anders Olofsson, Fredrik Almqvist

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dan E AdolfssonUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Mohit TyagiUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Pardeep SinghUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Adrian DeuschmannUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Jörgen ÅdénUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Anna L GharibyanUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Sanduni Wasana JayaweeraUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Anders E G LindgrenUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Anders OlofssonUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.
Fredrik AlmqvistUmeå University, Department of Chemistry, 901 87 Umeå, Sweden.ORCID 0000-0003-4646-0216
Umeå University · SE

Funding

Chemical disarming of drug resistance in Mycobacterium tuberculosisR01AI134847 · NIAID · WASHINGTON UNIVERSITY · PI ALMQVIST, FREDRIK, STALLINGS, CHRISTINA LEIGH · 2018 to 2021
$2.7M
NIAID NIH HHS R01 AI134847
6 · The paper itself

Abstract

A BF

Indexed as

alpha-SynucleinAmyloidAmyloid beta-PeptidesPyridones2-hydroxypyridinealpha-SynucleinAmyloidAmyloid beta-PeptidesPyridones

Identifiers

PMID33099999
PMCPMC7660745
OpenAlexW3094128160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.