Evidence map›Paper›PMID 33099745›Full record

ReviewMolecular and cellular biochemistry2021

Aristocratic human papillomavirus drove cervical cancer: a study of the therapeutic potential of the combination of interferon with zinc.

Yun-He Gao, Lei Yu, Zhong-Shan Liu, Yun-Feng Li

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yun-He GaoDepartment of Pathology, Second Hospital of Jilin University, Changchun, 130022, Jilin, China.
Lei YuDepartment of Radiation Oncology, Second Hospital of Jilin University, Changchun, 130022, Jilin, China.
Zhong-Shan LiuDepartment of Radiation Oncology, Second Hospital of Jilin University, Changchun, 130022, Jilin, China.
Yun-Feng LiDepartment of Radiation Oncology, Second Hospital of Jilin University, Changchun, 130022, Jilin, China. liyeng_fun@zoho.com.cn.ORCID http://orcid.org/0000-0002-6238-4789
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus (HPV) infection is related to cancer growth of vaginal, cervical, vulva, penile, anogenital, and non-genital oropharyngeal sites. HPV, as a sexually transmitted virus, infects all sexes similarly but with more significant pathological risks in women. This accounts for high mortality due to late detection and poor prognosis. The initial development and eventual progress of this cancer type depend entirely on three main oncogenes E5, E6 and E7, constitutively expressed to lead to carcinogenesis. Despite an opportunity for pharmacological therapy, there is still a shortage of medical treatment that may remove HPV from infected lesions. This study offers a concise summary of the nature of the issue and the current status of work on potential lead molecules and therapeutic approaches that show the capacity of HPV therapies to counteract the roles of deregulation of E5, E6, and E7.

Indexed as

Antiviral AgentsDrug Therapy, CombinationFemaleHumansInterferonsPapillomaviridaePapillomavirus InfectionsTrace ElementsUterine Cervical NeoplasmsZincAntiviral AgentsInterferonsTrace ElementsZincHuman papillomavirusInsulin-like growth factorInterferonMAPKProtein kinase BReceptor protein tyrosine kinasesRetinoblastoma

Identifiers

PMID33099745
OpenAlexW3093703153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.