Evidence map›Paper›PMID 33099721›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Migraine neuroscience: from experimental models to target therapy.

Rosaria Greco, Chiara Demartini, Roberto De Icco, Daniele Martinelli, Alessia Putortì, Cristina Tassorelli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Common Clinical and Molecular Pathways between Migraine and Sarcoidosis.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rosaria GrecoHeadache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy. rosaria.greco@mondino.it.
Chiara DemartiniHeadache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy.
Roberto De IccoHeadache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy.
Daniele MartinelliHeadache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy.
Alessia PutortìHeadache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy.
Cristina TassorelliHeadache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy.
Fondazione Istituto Neurologico Nazionale Casimiro Mondino · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine sciences have witnessed tremendous advances in recent years. Pre-clinical and clinical experimental models have contributed significantly to provide useful insights into the brain structures that mediate migraine attacks. These models have contributed to elucidate the role of neurotransmission pathways and to identify the role of important molecules within the complex network involved in migraine pathogenesis. The contribution and efforts of several research groups from all over the world has ultimately lead to the generation of novel therapeutic approaches, specifically targeted for the prevention of migraine attacks, the monoclonal antibodies directed against calcitonin gene-related peptide or its receptor. These drugs have been validated in randomized placebo-controlled trials and are now ready to improve the lives of a large multitude of migraine sufferers. Others are in the pipeline and will soon be available.

Indexed as

Calcitonin Gene-Related Peptide Receptor AntagonistsMigraine DisordersAntibodies, MonoclonalCalcitonin Gene-Related PeptideHumansModels, TheoreticalAntibodies, MonoclonalCalcitonin Gene-Related PeptideCalcitonin Gene-Related Peptide Receptor AntagonistsAnimal modelsCalcitonin genre-related peptideHuman modelsNitric oxideTrigeminal stimulation

Identifiers

PMID33099721
OpenAlexW3094213955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.