Evidence map›Paper›PMID 33099405›Full record

ArticleCell systems2020

μDamID: A Microfluidic Approach for Joint Imaging and Sequencing of Protein-DNA Interactions in Single Cells.

Nicolas Altemose, Annie Maslan, Carolina Rios-Martinez, Andre Lai, Jonathan A White, Aaron Streets

Abstract read
In one paragraph

Article in Cell systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicolas AltemoseDepartment of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Annie MaslanDepartment of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Carolina Rios-MartinezDepartment of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Andre LaiDepartment of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Jonathan A WhiteDepartment of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA.
Aaron StreetsDepartment of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: astreets@berkeley.edu.

Funding

OPTICAL, FLUIDIC, AND MOLECULAR TECHNOLOGIES FOR SINGLE-CELL OMICSR35GM124916 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Aaron Streets · 2017 to 2026
$3.4M
Howard Hughes Medical InstituteNIGMS NIH HHS R35 GM124916
6 · The paper itself

Abstract

DNA adenine methyltransferase identification (DamID) measures a protein's DNA-binding history by methylating adenine bases near each protein-DNA interaction site and then selectively amplifying and sequencing these methylated regions. Additionally, these interactions can be visualized using

Indexed as

AdenineCell NucleusChromatinDNADNA-Binding ProteinsDNA MethylationGenomicsHEK293 CellsHumansLamin Type BMicrofluidicsReceptors, PurinergicSequence Analysis, DNASingle-Cell AnalysisAdenineChromatinDNADNA-Binding ProteinsLamin Type BReceptors, Purinergicepigenomicsmicrofluidicsnuclear organizationsingle-cell sequencing

Identifiers

PMID33099405
PMCPMC7588622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.