ArticleHuman brain mapping2021
Multimodal imaging of brain reorganization in hearing late learners of sign language.
Article in Human brain mapping, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Resting-State Coactivation Patterns of Language Reorganization in Brain Tumors.Neural plasticity · 2026Article
- Similar Computational Hierarchies for Reading and Speech in the Occipital Cortex of Sighed and Blind: Converging Evidence from fMRI and Chronometric TMS.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Distinct neural representations of different linguistic components following sign language learning.Communications biology · 2025Article
- Neural adaptations in short-term learning of sign language revealed by fMRI and DTI.Scientific reports · 2025Article
- Neural underpinnings of sentence reading in deaf, native sign language users.Brain and language · 2024Article
- Word frequency and reading demands modulate brain activation in the inferior frontal gyrus.Scientific reports · 2023Article
- Sign and Spoken Language Processing Differences in the Brain: A Brief Review of Recent Research.Annals of neurosciences · 2022Review
- Associations Between Sign Language Skills and Resting-State Functional Connectivity in Deaf Early Signers.Frontiers in psychology · 2022Article
- Temporal Dynamics of Brain White Matter Plasticity in Sighted Subjects during Tactile Braille Learning: A Longitudinal Diffusion Tensor Imaging Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Multimodal imaging of brain reorganization in hearing late learners of sign language.Human brain mapping · 2021Article
- The role of the superior parietal lobule in lexical processing of sign language: Insights from fMRI and TMS.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- How Musical Training Shapes the Adult Brain: Predispositions and Neuroplasticity.Frontiers in neuroscience · 2021Review
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Authors and funding
10 authors.
Funding
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Abstract
The neural plasticity underlying language learning is a process rather than a single event. However, the dynamics of training-induced brain reorganization have rarely been examined, especially using a multimodal magnetic resonance imaging approach, which allows us to study the relationship between functional and structural changes. We focus on sign language acquisition in hearing adults who underwent an 8-month long course and five neuroimaging sessions. We assessed what neural changes occurred as participants learned a new language in a different modality-as reflected by task-based activity, connectivity changes, and co-occurring structural alterations. Major changes in the activity pattern appeared after just 3 months of learning, as indicated by increases in activation within the modality-independent perisylvian language network, together with increased activation in modality-dependent parieto-occipital, visuospatial and motion-sensitive regions. Despite further learning, no alterations in activation were detected during the following months. However, enhanced coupling between left-lateralized occipital and inferior frontal regions was observed as the proficiency increased. Furthermore, an increase in gray matter volume was detected in the left inferior frontal gyrus which peaked at the end of learning. Overall, these results showed complexity and temporal distinctiveness of various aspects of brain reorganization associated with learning of new language in different sensory modality.
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