Evidence map›Paper›PMID 33098553›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2020

Covariables of Myocardial Function in Women and Men with Increased Body Mass Index.

Nadia Pristaj, Sahrai Saeed, Helga Midtbø, Hilde Halland, Knut Matre, Eva Gerdts

Registry-linked trialAbstract read
In one paragraph

Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02805478 (Fat-Associated Cardiovascular Organ Dysfunction), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02805478 completednot on this map

Fat-Associated Cardiovascular Organ Dysfunction

TypeobservationalSponsorHaukeland University HospitalRan2009 to 2017Enrolled618ConditionsOverweight, ObesityArmsThere is no intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadia PristajDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway.
Sahrai SaeedDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Helga MidtbøDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Hilde HallandDepartment of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Knut MatreDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway.
Eva GerdtsDepartment of Clinical Science, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway. eva.gerdts@med.uib.no.ORCID http://orcid.org/0000-0003-4109-2311

Funding

Helse Vest 911402
6 · The paper itself

Abstract

introductionSex-difference in types of cardiac organ damage has been reported in subjects with increased body mass index (BMI). However less is known about sex-differences in left ventricular (LV) myocardial function assessed by global longitudinal strain (GLS) in these subjects.

methods493 subjects (mean age 47 ± 9 years, 61% women) with BMI > 27.0 kg/m

resultsWomen had higher prevalence of increased waist circumference (99% vs. 82%), lower prevalence of hypertension (59 vs. 74%), and lower serum triglycerides (1.3 ± 0.7 vs. 1.7 ± 0.9 mmol/L) and carotid-femoral PWV (7.3 ± 1.6 vs. 7.7 ± 1.6 m/s) compared to men (all p < 0.05). Women also had higher (more negative) GLS compared to men (- 19.9 ± 3.0 vs. - 18.6 ± 3.0%, p < 0.001), while EF did not differ between sexes. In multivariable linear regression analyses, lower GLS in women was associated with higher waist circumference and PWV and with lower EF (all p < 0.05). In men, lower GLS was associated with higher waist circumference and HOMA-IR, and with lower EF (all p < 0.05).

conclusionsAmong subjects with increased BMI, GLS was higher in women than men. Lower GLS was associated with abdominal obesity in both sexes, and with impaired glucose metabolism in men, and with higher arterial stiffness in women.

trial registrationhttps://www.clinicaltrials.gov NCT02805478, first registered 20.06.16.

Indexed as

Body Mass IndexHealth Status DisparitiesStroke VolumeVentricular Function, LeftAdultBiomarkersBlood GlucoseCross-Sectional StudiesFemaleGlucose Metabolism DisordersHumansMaleMiddle AgedNorwayObesity, AbdominalPrevalenceBiomarkersBlood GlucoseArterial stiffnessGlobal longitudinal strainHypertensionObesitySex

Identifiers

PMID33098553
PMCPMC7661414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.