Evidence map›Paper›PMID 33098536›Full record

ArticleInternational journal of computer assisted radiology and surgery2021

Interactive editing of virtual chordae tendineae for the simulation of the mitral valve in a decision support system.

Lars Walczak, Lennart Tautz, Mathias Neugebauer, Joachim Georgii, Isaac Wamala, Simon Sündermann, Volkmar Falk, Anja Hennemuth

Abstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lars WalczakFraunhofer MEVIS, Bremen, Germany. lars.walczak@mevis.fraunhofer.de.ORCID http://orcid.org/0000-0001-6124-0671
Lennart TautzFraunhofer MEVIS, Bremen, Germany.
Mathias NeugebauerFraunhofer MEVIS, Bremen, Germany.
Joachim GeorgiiFraunhofer MEVIS, Bremen, Germany.
Isaac WamalaGerman Heart Institute Berlin-DHZB, Berlin, Germany.
Simon SündermannCharité-Universitätsmedizin Berlin, Berlin, Germany.
Volkmar FalkCharité-Universitätsmedizin Berlin, Berlin, Germany.
Anja HennemuthFraunhofer MEVIS, Bremen, Germany.

Funding

Bundesministerium für Bildung und Forschung 03VP00852
6 · The paper itself

Abstract

purposeDecision support systems for mitral valve disease are an important step toward personalized surgery planning. A simulation of the mitral valve apparatus is required for decision support. Building a model of the chordae tendineae is an essential component of a mitral valve simulation. Due to image quality and artifacts, the chordae tendineae cannot be reliably detected in medical imaging.

methodsUsing the position-based dynamics framework, we are able to realistically simulate the opening and closing of the mitral valve. Here, we present a heuristic method for building an initial chordae model needed for a successful simulation. In addition to the heuristic, we present an interactive editor to refine the chordae model and to further improve pathology reproduction as well as geometric approximation of the closed valve.

resultsFor evaluation, five mitral valves were reconstructed based on image sequences of patients scheduled for mitral valve surgery. We evaluated the approximation of the closed valves using either just the heuristic chordae model or a manually refined model. Using the manually refined models, prolapse was correctly reproduced in four of the five cases compared to two of the five cases when using the heuristic. In addition, using the editor improved the approximation in four cases.

conclusionsOur approach is suitable to create realistically parameterized mitral valve apparatus reconstructions for the simulation of normally and abnormally closing valves in a decision support system.

Indexed as

Computer SimulationModels, AnatomicChordae TendineaeHumansMitral ValveMitral Valve InsufficiencyDecision supportMitral valvePosition-based dynamics

Identifiers

PMID33098536
PMCPMC7822807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.