ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021
Proposed radiological score for the evaluation of isolated fourth ventricle treated by endoscopic aqueductoplasty.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 3 citations in OpenAlex.
- Third ventriculostomy and endoscopic aqueductoplasty in a child with isolated fourth ventricle after intraventricular hemorrhage of prematurity.Surgical neurology international · 2026Article
- Radiologic and clinical outcome of isolated fourth ventricle following post-hemorrhagic hydrocephalus in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Neuroendoscopic Approach of a Massive Bilateral Chronic Subdural Hematoma in a Child Using a Single Burr Hole.Cureus · 2021Article
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3 authors at 2 institutions in 1 country.
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Abstract
purposeEvidence supporting the effectiveness of endoscopic aqueductoplasty (EA) for the treatment of isolated fourth ventricle (IFV) is limited to small surgical series of cases. Additionally, studies adopted different radiological outcome criteria, which makes it difficult to compare outcomes accurately. Thus, we aimed to develop a radiological score (RS) as an alternative assessment method for EA.
methodsThe cases of 20 consecutive pediatric patients harboring IFV and treated by EA were retrospectively reviewed. Clinical data and pre- and 1-year postoperative brain images were analyzed. The RS was based on the enlargement of the fourth ventricle and deformation of the cerebellum and brainstem. After randomization, three experts, blinded to patient outcomes, analyzed the brain images and established a consensus for the values of the score. Outcomes were validated by comparing the maximum anteroposterior distance of the fourth ventricle using the RS, pediatric functional status score, and clinical symptoms.
resultsThe RS was strongly correlated with the anteroposterior distance of the fourth ventricle (Pearson's coefficient = 0.78), and the mean RS dropped from 6.15 to 3.90 (p < 0.001) 1 year after EA. Upward extension (p = 0.021) and brainstem deformation (p = 0.010) were the most significant improved features. There was agreement among RS and symptom improvement in 16 children (80%) and the pediatric functional status score in 14 children (70%).
conclusionIn this study, the proposed radiological score proved to be an accurate tool for the evaluation of IFV treatment with EA.
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