Evidence map›Paper›PMID 33098368›Full record

ArticleGeriatrics & gerontology international2020

Delirium, functional decline and quality of life after transcatheter aortic valve implantation: An explorative study.

Sara J Beishuizen, Suzanne Festen, Yvette E Loonstra, Hindrik W van der Werf, Sophia E de Rooij, Barbara C van Munster

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Geriatrics & gerontology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sara J BeishuizenUniversity Center of Geriatric Medicine, University Medical Center Groningen, Groningen, the Netherlands.ORCID https://orcid.org/0000-0001-6885-4430
Suzanne FestenUniversity Center of Geriatric Medicine, University Medical Center Groningen, Groningen, the Netherlands.
Yvette E LoonstraUniversity Center of Geriatric Medicine, University Medical Center Groningen, Groningen, the Netherlands.
Hindrik W van der WerfDepartment of Cardiology, University Medical Center Groningen, Groningen, the Netherlands.
Sophia E de RooijUniversity Center of Geriatric Medicine, University Medical Center Groningen, Groningen, the Netherlands.
Barbara C van MunsterUniversity Center of Geriatric Medicine, University Medical Center Groningen, Groningen, the Netherlands.
University Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTranscatheter aortic valve implantation (TAVI) has become an important treatment option for older patients with severe aortic stenosis. However, not all patients benefit from this procedure in terms of functional outcome and quality of life. This complicates patient selection and shared decision-making. Postoperative delirium might negatively affect patient outcomes after TAVI. We therefore studied the potential relationship between postoperative delirium and functional outcome, and how this impacts quality of life after TAVI.

methodsThis was a prospective cohort study of 91 consecutive patients undergoing TAVI between 2015 and 2017 at an academic medical center. All patients underwent a Comprehensive Geriatric Assessment before TAVI. Delirium symptoms were assessed daily during hospitalization. Follow up was carried out between 6 and 12 months postprocedure. The primary outcome was functional decline or death at follow up. Secondarily, we measured quality of life at follow up.

resultsThe incidence of postoperative delirium was 15.4%. In total, 38.5% of patients experienced functional decline, and 11.0% died during a median follow-up period of 7 months. Delirium resulted in a fourfold increased odds of the combined outcome of functional decline or death. Quality of life was lower in patients that experienced this outcome.

conclusionIn a cohort of TAVI patients, functional decline or death was a frequent outcome in the first year postprocedure. Postoperative delirium increased the odds for this outcome substantially. This suggests that delirium risk should be an important factor to consider in shared decision-making for TAVI patients. Geriatr Gerontol Int 2020; 20: 1202-1207.

Indexed as

DeliriumHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve ReplacementAgedGeriatric AssessmentHumansProspective StudiesQuality of LifeRisk FactorsTreatment Outcomeactivities of daily livingcardiovascular surgerydeliriumquality of lifetranscatheter aortic valve implantation

Identifiers

PMID33098368
PMCPMC7756254
OpenAlexW3093921986

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.