Evidence map›Paper›PMID 33098019›Full record

ArticleEuropean journal of clinical pharmacology2021

Switching from a traditional undergraduate programme in (clinical) pharmacology and therapeutics to a problem-based learning programme.

David J Brinkman, Teresa Monteiro, Emilia C Monteiro, Milan C Richir, Michiel A van Agtmael, Jelle Tichelaar

Abstract readComparative Study
In one paragraph

Article in European journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  4. Reimagining pharmacology education.Pharmacological reviews · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David J Brinkman *Section Pharmacotherapy, Department of Internal Medicine, Amsterdam University Medical Centers, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands. d.brinkman@amsterdamumc.nl.ORCID https://orcid.org/0000-0003-3816-6375
Teresa Monteiro *Faculdade de Ciências Médicas, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal.
Emilia C MonteiroFaculdade de Ciências Médicas, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal.
Milan C RichirSection Pharmacotherapy, Department of Internal Medicine, Amsterdam University Medical Centers, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands.
Michiel A van AgtmaelSection Pharmacotherapy, Department of Internal Medicine, Amsterdam University Medical Centers, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands.
Jelle TichelaarSection Pharmacotherapy, Department of Internal Medicine, Amsterdam University Medical Centers, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe pharmacology and clinical pharmacology and therapeutics (CPT) education during the undergraduate medical curriculum of NOVA Medical School, Lisbon, Portugal, was changed from a traditional programme (i.e. discipline-based, lectures) to a problem-based learning (PBL) programme (i.e. integrated, case-based discussions) without an increase in teaching hours. The aim of this study was to investigate whether this change improved the prescribing competencies of final-year medical students.

methodsFinal-year students from both programmes (2015 and 2019) were invited to complete a validated prescribing assessment and questionnaire. The assessment comprised 24 multiple-choice questions in three subdomains (working mechanism, side-effects and interactions/contraindications), and five clinical case scenarios of common diseases. The questionnaire focused on self-reported prescribing confidence, preparedness for future prescribing task and education received.

resultsIn total, 36 (22%) final-year medical students from the traditional programme and 54 (23%) from the PBL programme participated. Overall, students in the PBL programme had significantly higher knowledge scores than students in the traditional programme (76% (SD 9) vs 67% (SD 15); p = 0.002). Additionally, students in the PBL programme made significantly fewer inappropriate therapy choices (p = 0.023) and fewer erroneous prescriptions than did students in the traditional programme (p = 0.27). Students in the PBL programme felt more confident in prescribing, felt better prepared for prescribing as junior doctor and completed more drug prescriptions during their medical training.

conclusionChanging from a traditional programme to an integrated PBL programme in pharmacology and CPT during the undergraduate medical curriculum may improve the prescribing competencies of final-year students.

Indexed as

AdultClinical CompetenceCurriculumEducation, Medical, UndergraduateFemaleHumansMalePharmacology, ClinicalPortugalPractice Patterns, Physicians'Problem-Based LearningStudents, MedicalSurveys and QuestionnairesYoung AdultClinical pharmacologyMedical curriculumPrescribingStudentsTherapeuticsUndergraduate

Identifiers

PMID33098019
PMCPMC7867513

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.