SynthesisScientific reports2020
Combined healthy lifestyle factors are more beneficial in reducing cardiovascular disease in younger adults: a meta-analysis of prospective cohort studies.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Combined Effect of Healthy Lifestyle Factors and Risks of Colorectal Adenoma, Colorectal Cancer, and Colorectal Cancer Mortality: Systematic Review and Meta-Analysis.Frontiers in oncology · 2022Pooled it
- Pooled it
- Adiposity-Metabolic Discordance Identifies Cardiometabolically Heterogeneous Profiles in Normal-Weight Adults: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- ADHD and metabolic syndrome: behavioral and weight-related pathways to cardiovascular risk.European archives of psychiatry and clinical neuroscience · 2026Article
- Dual-trajectories of Systolic Blood Pressure and Modified Life's Essential 8 With Gastrointestinal Cancer and All-Cause Mortality: A Prospective Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Exploratory assessment of the correlates of lifestyle medicine among Spanish university students: UNILIFE-M study.BMC public health · 2026Article
- A latent class analysis of cardiometabolic risk factors and the predicted prevalence of subclinical atherosclerosis in middle-aged Swedish adults.Scientific reports · 2026Article
- Modeling the Impact of Behavior Changes on Mortality Attributable to Non-communicable Diseases in Canada.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026Article
- The Interaction of Health Behaviors and Cardiovascular Diseases: Investigating Morbidity Risks of Disparities in U.S. Adults.Healthcare (Basel, Switzerland) · 2025Article
- Movement and dietary behaviours and mental health among university students: the Health@NUS study.BMC public health · 2025Observational
- Healthy lifestyles are associated with alleviating the single-nucleotide polymorphism-based genetic risks of ischaemic stroke, intracerebral haemorrhage and myocardial infarction.Stroke and vascular neurology · 2025Article
- Mediation role of health behaviours in the relation between mental resilience and cardiovascular risk in young adults with a diagnosed congenital heart defect.BMC public health · 2025Observational
- Cardiovascular disease risk factors and the ten-year Cardiovascular disease risk among employees of a public university in Blantyre, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2025Article
- Unraveling temporal patterns of diagnostic markers and comorbidities in Alzheimer's disease: Insights from large-scale data.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Influence of Lifestyle Modifications on Cardiovascular Outcomes in Older Adults: Findings from a Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Changes in Cardiovascular Health, Genetic Risk, and Cardiometabolic Diseases: Evidence From a Large-Scale Cohort Study.Journal of the American Heart Association · 2025Article
- A multivariate analysis of reported quality of life among medical students in Jordan using the WHOQOL-BREF.Journal of education and health promotion · 2025Article
- Association of Life's Simple 7 lifestyle metric with cardiometabolic disease-free life expectancy in older British men.Communications medicine · 2024Article
- Is the time below 90% of SpOSleep & breathing = Schlaf & Atmung · 2024Article
- Trajectories of lifestyle patterns from 2 to 8 years of age and cardiometabolic risk in children: the GUSTO study.The international journal of behavioral nutrition and physical activity · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine the association between combined lifestyle factors, including healthy diet, moderate alcohol consumption, non-smoking, physical activity, and optimal weight, and cardiovascular disease (CVD) risk among younger and older adults. We conducted a literature search using PubMed, EMBASE, Cochrane Library, and EBSCO databases up to November 30, 2019 and performed dose-response analysis, subgroup analysis and meta-regression with odds ratios and 95% confidence intervals (CIs). Twenty cohort studies involving 1,090,261 participants with 46,288 cardiovascular events and mean follow-up duration of 12.33 years were included. Compared with the group with the lowest number of healthy lifestyle factors, the group with the highest number had lower CVD risk [pooled hazard ratio, 0.37 (95% CI 0.31-0.43)]. With age as an effect modifier, the lifetime risk of CVD was 0.31 (95% CI 0.24-0.41) at age 37.1-49.9 years, 0.36 (95% CI 0.30-0.45) at age 50.0-59.9 years and 0.49 (95% CI 0.38-0.63) at age 60.0-72.9 years. The hazard ratio of CVD significantly increased from 37.1 to 72.9 years of age [slope in multivariate meta-regression: 0.01 (95% CI < 0.001-0.03; p = 0.042)]. Younger adults have more cardiovascular benefits from combined healthy lifestyle factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.