ArticleScientific reports2020
Interactions between the microbiome and mating influence the female's transcriptional profile in Drosophila melanogaster.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- A novel female reproductive organ differentiates insemination and postmating responses in bedbugs.Molecular biology and evolution · 2026Article
- Alteration of the Microbiome is Associated with Changes in Mating and Locomotion in Callosobruchus maculatus.Microbial ecology · 2026Article
- Bacterial genome reconstruction and community profiling in Neotropical Drosophila.Scientific reports · 2026Article
- Life history drives the assembly of the bacterial community associated with the Horn fly, Haematobia irritans L. (Diptera: Muscidae).Archives of microbiology · 2026Article
- Microbial metabolites as engines of behavioral variation across animals.Gut microbes · 2025Review
- Microbiome composition shapes temperature tolerance in a Hawaiian picture-winged Drosophila.The Journal of experimental biology · 2025Article
- Semen adaptation to microbes in an insect.Evolution letters · 2024Article
- Insect-microbe interactions and their influence on organisms and ecosystems.Ecology and evolution · 2024Review
- Neurobiology of Pathogen Avoidance and Mate Choice: Current and Future Directions.Animals : an open access journal from MDPI · 2024Review
- Beneficial commensal bacteria promote Drosophila growth by downregulating the expression of peptidoglycan recognition proteins.iScience · 2022Article
- Review
- Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract.BMC genomics · 2021Article
- Characterization of the reproductive tract bacterial microbiota of virgin, mated, and blood-fed Aedes aegypti and Aedes albopictus females.Parasites & vectors · 2021Article
- Differences in Postmating Transcriptional Responses between Conspecific and Heterospecific Matings in Drosophila.Molecular biology and evolution · 2021Article
- Differences in Gut Microbiome Composition Between Sympatric Wild and Allopatric Laboratory Populations of Omnivorous Cockroaches.Frontiers in microbiology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Drosophila melanogaster females undergo a variety of post-mating changes that influence their activity, feeding behavior, metabolism, egg production and gene expression. These changes are induced either by mating itself or by sperm or seminal fluid proteins. In addition, studies have shown that axenic females-those lacking a microbiome-have altered fecundity compared to females with a microbiome, and that the microbiome of the female's mate can influence reproductive success. However, the extent to which post-mating changes in transcript abundance are affected by microbiome state is not well-characterized. Here we investigated fecundity and the post-mating transcript abundance profile of axenic or control females after mating with either axenic or control males. We observed interactions between the female's microbiome and her mating status: transcripts of genes involved in reproduction and genes with neuronal functions were differentially abundant depending on the females' microbiome status, but only in mated females. In addition, immunity genes showed varied responses to either the microbiome, mating, or a combination of those two factors. We further observed that the male's microbiome status influences the fecundity of both control and axenic females, while only influencing the transcriptional profile of axenic females. Our results indicate that the microbiome plays a vital role in the post-mating switch of the female's transcriptome.
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