Evidence map›Paper›PMID 33097732›Full record

ArticleNature communications2020

The desensitization pathway of GABA

Marc Gielen, Nathalie Barilone, Pierre-Jean Corringer

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Discovery and mechanism of negative allosteric modulation of the α7 nicotinic acetylcholine receptor by nanobodies.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Massive Activation of GABABiomolecules · 2025
    Review
  5. Article
  6. Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state modeling.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. GABAMolecular cell · 2025
    Article
  8. Understanding paralogous epilepsy-associated GABAProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Proline substitutions in the ASIC1 β11-12 linker slow desensitization.bioRxiv : the preprint server for biology · 2024
    Article
  12. Glutamate Spillover Dynamically Strengthens Gabaergic Synaptic Inhibition of the Hypothalamic Paraventricular Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  13. Article
  14. Biomolecules · 2023
    Article
  15. Article
  16. Article
  17. Physiological Role of ATPase for GABAInternational journal of molecular sciences · 2022
    Article
  18. Article
  19. The Influence of AA29504 on GABANeurochemical research · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marc GielenChannel Receptors Unit, Institut Pasteur, CNRS UMR 3571, 25 rue du Docteur Roux, 75015, Paris, France. marc.gielen@pasteur.fr.ORCID 0000-0003-0941-4325
Nathalie BariloneChannel Receptors Unit, Institut Pasteur, CNRS UMR 3571, 25 rue du Docteur Roux, 75015, Paris, France.
Pierre-Jean CorringerChannel Receptors Unit, Institut Pasteur, CNRS UMR 3571, 25 rue du Docteur Roux, 75015, Paris, France.
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GABA

Indexed as

AnimalsComputer SimulationIon ChannelsIon TransportKineticsModels, MolecularMolecular ConformationMutationNervous SystemOocytesProtein ConformationProtein SubunitsReceptors, GABA-ASynaptic TransmissionXenopus laevisIon ChannelsProtein SubunitsReceptors, GABA-A

Identifiers

PMID33097732
PMCPMC7585415
OpenAlexW3094555361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.