ArticleProceedings of the National Academy of Sciences of the United States of America2020
Simple transformations capture auditory input to cortex.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Temporal recurrence as a general mechanism to explain neural responses in the auditory system.Communications biology · 2025Article
- Neural Response Attenuates with Decreasing Inter-Onset Intervals Between Sounds in a Natural Soundscape.eNeuro · 2025Article
- Synaptic Function and Sensory Processing in ZDHHC9-Associated Neurodevelopmental Disorder: A Mechanistic Account.The European journal of neuroscience · 2025Article
- Prediction of future input explains lateral connectivity in primary visual cortex.Current biology : CB · 2025Article
- Modelling neural coding in the auditory midbrain with high resolution and accuracy.Nature machine intelligence · 2025Article
- Exploring Relevant Features for EEG-Based Investigation of Sound Perception in Naturalistic Soundscapes.eNeuro · 2025Article
- A general model unifying the adaptive, transient and sustained properties of ON and OFF auditory neural responses.PLoS computational biology · 2024Article
- Dissociable Roles of the Auditory Midbrain and Cortex in Processing the Statistical Features of Natural Sound Textures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Eelbrain, a Python toolkit for time-continuous analysis with temporal response functions.eLife · 2023Article
- Large-scale electrophysiology and deep learning reveal distorted neural signal dynamics after hearing loss.eLife · 2023Article
- Quantitative models of auditory cortical processing.Hearing research · 2023Review
- Two stages of bandwidth scaling drives efficient neural coding of natural sounds.PLoS computational biology · 2023Article
- Article
- Decoding violated sensory expectations from the auditory cortex of anaesthetised mice: Hierarchical recurrent neural network depicts separate 'danger' and 'safety' units.The European journal of neuroscience · 2022Article
- Cortical adaptation to sound reverberation.eLife · 2022Article
- A comparative study of eight human auditory models of monaural processing.Acta acustica. European Acoustics Association · 2022Article
- Sensitivity of neural responses in the inferior colliculus to statistical features of sound textures.Hearing research · 2021Article
- The Elusive Cochlear Filter: Wave Origin of Cochlear Cross-Frequency Masking.Journal of the Association for Research in Otolaryngology : JARO · 2021Article
- Communication breakdown: Limits of spectro-temporal resolution for the perception of bat communication calls.Scientific reports · 2021Article
- Neuronal selectivity to complex vocalization features emerges in the superficial layers of primary auditory cortex.PLoS biology · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Sounds are processed by the ear and central auditory pathway. These processing steps are biologically complex, and many aspects of the transformation from sound waveforms to cortical response remain unclear. To understand this transformation, we combined models of the auditory periphery with various encoding models to predict auditory cortical responses to natural sounds. The cochlear models ranged from detailed biophysical simulations of the cochlea and auditory nerve to simple spectrogram-like approximations of the information processing in these structures. For three different stimulus sets, we tested the capacity of these models to predict the time course of single-unit neural responses recorded in ferret primary auditory cortex. We found that simple models based on a log-spaced spectrogram with approximately logarithmic compression perform similarly to the best-performing biophysically detailed models of the auditory periphery, and more consistently well over diverse natural and synthetic sounds. Furthermore, we demonstrated that including approximations of the three categories of auditory nerve fiber in these simple models can substantially improve prediction, particularly when combined with a network encoding model. Our findings imply that the properties of the auditory periphery and central pathway may together result in a simpler than expected functional transformation from ear to cortex. Thus, much of the detailed biological complexity seen in the auditory periphery does not appear to be important for understanding the cortical representation of sound.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.